Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 13/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 14/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23313266 | 0.81 | METTL3 (0.60) | METTL3PRMT5 | |
| SCHEMBL25017607 | 0.74 | METTL3 (0.75) | METTL3PRMT5 | |
| SCHEMBL25015993 | 0.74 | METTL3 (0.70) | METTL3PRMT5 | |
| SCHEMBL23313243 | 0.73 | METTL3 (0.57) | METTL3PRMT5 | |
| SCHEMBL23313158 | 0.73 | PRMT5 (0.82) | METTL3PRMT5 | |
| SCHEMBL23313247 | 0.68 | PRMT5 (0.62) | METTL3PRMT5 | |
| SCHEMBL25015586 | 0.67 | PRMT5 (0.73) | METTL3PRMT5 | |
| SCHEMBL23313248 | 0.67 | PRMT5 (0.57) | METTL3PRMT5 | |
| SCHEMBL14644481 | 0.67 | ADK (0.43) | METTL3PRMT5 | |
| SCHEMBL25015953 | 0.66 | METTL3 (0.81) | METTL3PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2021079196-A2 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2021-04-29 | — | — | WO | disclosed |