SCHEMBL2331370

SCHEMBL2331370

CCCCNC(=O)C1CC(C)CCC1C(C)C

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 6/20 0.58
EPHX1 P07099 1/20 0.53
POLB P06746 1/20 0.40
TRPA1 O75762 2/20 0.40
NAAA Q02083 1/20 0.40
PRCP P42785 1/20 0.39
OPRM1 P35372 1/20 0.39
GNAI3 P08754 1/20 0.38
GNAO1 P09471 1/20 0.38
GNAI1 P63096 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6872038 0.96 TRPM8 (0.56) TRPM8EPHX1POLBNAAAPRCP
SCHEMBL6871778 0.94 TRPM8 (0.55) TRPM8EPHX1POLBNAAAPRCP
SCHEMBL6868953 0.94 TRPM8 (0.55) TRPM8EPHX1POLBNAAAPRCP
SCHEMBL18287153 0.94 TRPM8 (0.55) TRPM8EPHX1POLBNAAAPRCP
SCHEMBL6862982 0.91 TRPM8 (0.60) TRPM8EPHX1TRPA1
SCHEMBL18547556 0.90 TRPM8 (0.61) TRPM8EPHX1POLBTRPA1
SCHEMBL18583870 0.90 TRPM8 (0.61) TRPM8EPHX1POLBTRPA1
SCHEMBL11418730 0.89 TRPM8 (0.54) TRPM8EPHX1TRPA1
SCHEMBL18583469 0.87 EPHX1 (0.55) TRPM8EPHX1TRPA1
Hydrochloric Acid SCHEMBL18547896 0.86 EPHX1 (0.54) TRPM8EPHX1TRPA1GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2533760-A1 LIQUID COMPOSITION COMPRISING A NON-MENTHOL COOLING AGENT AND A THICKENER FOR TREATING A RESPIRATORY SYMPTOM The Procter & Gamble Company (US) 2012-12-19 EP claimed
WO-2011100267-A1 LIQUID COMPOSITION COMPRISING A NON-MENTHOL COOLING AGENT AND A THICKENER FOR TREATING A RESPIRATORY SYMPTOM THE PROCTER & GAMBLE COMPANY (US) 2011-08-18 WO claimed
WO-2023248187-A1 ORAL COMPOSITION COMPRISING A RECEPTOR MODULATOR Nicoventures Trading Limited (GB) 2023-12-28 WO disclosed
WO-2017048490-A1 A PROCESS FOR MAKING A DETERGENT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2017-03-23 WO disclosed
WO-2016094599-A1 A PROCESS FOR MAKING A CONSUMER GOODS PRODUCT COMPRISING A BENEFIT DELIVERY COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2016-06-16 WO disclosed
WO-2016094600-A1 A PROCESS FOR MAKING A CONSUMER GOODS PRODUCT COMPRISING A BENEFIT DELIVERY COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2016-06-16 WO disclosed
EP-2934119-A1 INSECT REPELLENT CLEANING COMPOSITION Henkel AG & Co. KGaA (DE) 2015-10-28 EP disclosed
WO-2014095541-A1 INSECT REPELLENT CLEANING COMPOSITION HENKEL AG & CO. KGAA (DE) 2014-06-26 WO disclosed
EP-1750525-A2 PHYSIOLOGICAL COOLING COMPOSITIONS Millennium Specialty Chemicals, Inc. (US) 2007-02-14 EP disclosed
WO-2005117811-A2 PHYSIOLOGICAL COOLING COMPOSITIONS MILLENNIUM SPECIALTY CHEMICALS (US) 2005-12-15 WO disclosed
EP-1311158-B1 COMPOSITION HAVING INSECT REPELLENT CHARACTERISTICS GIVAUDAN SA (CH) 2004-08-11 EP disclosed
US-20040028714-A1 Composition having insect repellent characteristics GIVAUDAN SA (CH) 2004-02-12 US disclosed
EP-1311158-A1 COMPOSITION HAVING INSECT REPELLENT CHARACTERISTICS Givaudan SA (CH) 2003-05-21 EP disclosed
WO-2002015692-A1 COMPOSITION HAVING INSECT REPELLENT CHARACTERISTICS GIVAUDAN SA (CH) 2002-02-28 WO disclosed
US-4391285-A Smoking article PHILIP MORRIS, INCORPORATED (US) 1983-07-05 US disclosed
US-4347855-A Method of making smoking articles PHILIP MORRIS INCORPORATED (US) 1982-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040028714-A1 Composition having insect repellent characteristics SUV39H1, PNMT, SUV39H2 TRPM8 36/4885EPHX1 690/4885POLB 3532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.