SCHEMBL6862982

SCHEMBL6862982

CCCNC(=O)C1CC(C)CCC1C(C)C

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 7/20 0.60
EPHX1 P07099 3/20 0.55
TRPA1 O75762 2/20 0.42
CHRNB2 P17787 1/20 0.42
CHRNB4 P30926 1/20 0.42
CHRNA3 P32297 1/20 0.42
CHRNA7 P36544 1/20 0.42
CHRNA4 P43681 1/20 0.42
TRPV1 Q8NER1 3/20 0.37
GRM4 Q14833 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18547556 0.92 TRPM8 (0.61) TRPM8EPHX1TRPA1TRPV1
SCHEMBL18583870 0.92 TRPM8 (0.61) TRPM8EPHX1TRPA1TRPV1
SCHEMBL2331370 0.91 TRPM8 (0.58) TRPM8EPHX1TRPA1
SCHEMBL6872038 0.90 TRPM8 (0.56) TRPM8EPHX1
SCHEMBL6871778 0.89 TRPM8 (0.55) TRPM8EPHX1
SCHEMBL6868953 0.89 TRPM8 (0.55) TRPM8EPHX1
SCHEMBL18287153 0.89 TRPM8 (0.55) TRPM8EPHX1
SCHEMBL24540533 0.88 TRPM8 (0.57) TRPM8EPHX1TRPA1TRPV1
SCHEMBL11411056 0.88 TRPM8 (0.57) TRPM8EPHX1TRPA1TRPV1
SCHEMBL3106213 0.88 TRPM8 (0.63) TRPM8EPHX1TRPA1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106659656-B Oral composition 狮王株式会社 2020-01-10 CN claimed
CN-106659656-B Oral composition 狮王株式会社 2020-01-10 CN disclosed
EP-2934119-A1 INSECT REPELLENT CLEANING COMPOSITION Henkel AG & Co. KGaA (DE) 2015-10-28 EP disclosed
WO-2014095541-A1 INSECT REPELLENT CLEANING COMPOSITION HENKEL AG & CO. KGAA (DE) 2014-06-26 WO disclosed
EP-1311158-B1 COMPOSITION HAVING INSECT REPELLENT CHARACTERISTICS GIVAUDAN SA (CH) 2004-08-11 EP disclosed
US-20040028714-A1 Composition having insect repellent characteristics GIVAUDAN SA (CH) 2004-02-12 US disclosed
EP-1311158-A1 COMPOSITION HAVING INSECT REPELLENT CHARACTERISTICS Givaudan SA (CH) 2003-05-21 EP disclosed
WO-2002015692-A1 COMPOSITION HAVING INSECT REPELLENT CHARACTERISTICS GIVAUDAN SA (CH) 2002-02-28 WO disclosed
US-4136163-A P-MENTHANE CARBOXAMIDES HAVING A PHYSIOLOGICAL COOLING EFFECT WILKINSON SWORD LIMITED (GB) 1979-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040028714-A1 Composition having insect repellent characteristics SUV39H1, PNMT, SUV39H2 TRPM8 36/4885EPHX1 690/4885TRPA1 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.