Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | PRCP | P42785 | 2/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871778 | 1.00 | TRPM8 (0.55) | TRPM8EPHX1NAAAPRCPGNAI3 | |
| SCHEMBL18287153 | 1.00 | TRPM8 (0.55) | TRPM8EPHX1NAAAPRCPGNAI3 | |
| SCHEMBL6872038 | 0.99 | TRPM8 (0.56) | TRPM8EPHX1NAAAPRCPGNAI3 | |
| SCHEMBL2331370 | 0.94 | TRPM8 (0.58) | TRPM8EPHX1NAAAPRCPGNAI3 | |
| SCHEMBL18547907 | 0.89 | TRPM8 (0.55) | TRPM8EPHX1NAAAPRCPPOLB | |
| SCHEMBL6862982 | 0.89 | TRPM8 (0.60) | TRPM8EPHX1 | |
| SCHEMBL18563060 | 0.88 | EPHX1 (0.52) | TRPM8EPHX1NAAAGNAI3GNAO1 | |
| SCHEMBL18583761 | 0.88 | EPHX1 (0.52) | TRPM8EPHX1NAAAGNAI3GNAO1 | |
| SCHEMBL18583870 | 0.87 | TRPM8 (0.61) | TRPM8EPHX1POLB | |
| SCHEMBL18547556 | 0.87 | TRPM8 (0.61) | TRPM8EPHX1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10981862-B2 | Physiological cooling compounds | SYMRISE, INC. (US) | 2021-04-20 | — | — | US | disclosed |
| US-10173966-B2 | Physiological cooling compounds | SYMRISE, INC. (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180179147-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | SYMRISE, INC. | 2018-06-28 | — | — | US | disclosed |
| US-20160355463-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | SYMRISE, INC. | 2016-12-08 | — | — | US | disclosed |
| US-20160355463-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | SYMRISE, INC. | 2016-12-08 | — | — | US | disclosed |
| EP-2934119-A1 | INSECT REPELLENT CLEANING COMPOSITION | Henkel AG & Co. KGaA (DE) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014095541-A1 | INSECT REPELLENT CLEANING COMPOSITION | HENKEL AG & CO. KGAA (DE) | 2014-06-26 | — | — | WO | disclosed |
| EP-1311158-B1 | COMPOSITION HAVING INSECT REPELLENT CHARACTERISTICS | GIVAUDAN SA (CH) | 2004-08-11 | — | — | EP | disclosed |
| US-20040028714-A1 | Composition having insect repellent characteristics | GIVAUDAN SA (CH) | 2004-02-12 | — | — | US | disclosed |
| EP-1311158-A1 | COMPOSITION HAVING INSECT REPELLENT CHARACTERISTICS | Givaudan SA (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002015692-A1 | COMPOSITION HAVING INSECT REPELLENT CHARACTERISTICS | GIVAUDAN SA (CH) | 2002-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981862-B2 | Physiological cooling compounds | TAS2R8, TAS2R3, TAS2R1 | TRPM8 29/4885EPHX1 2251/4885NAAA 650/4885 |
| US-10173966-B2 | Physiological cooling compounds | TAS2R8, TAS2R3, TAS2R1 | TRPM8 29/4885EPHX1 2251/4885NAAA 650/4885 |
| US-20160355463-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | TAS2R8, TAS2R3, TAS2R1 | TRPM8 29/4885EPHX1 2251/4885NAAA 650/4885 |
| US-20180179147-A1 | PHYSIOLOGICAL COOLING COMPOUNDS | TAS2R8, TAS2R3, TAS2R1 | TRPM8 29/4885EPHX1 2251/4885NAAA 650/4885 |
| US-20040028714-A1 | Composition having insect repellent characteristics | SUV39H1, PNMT, SUV39H2 | TRPM8 36/4885EPHX1 690/4885NAAA 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.