Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23315440 | 0.86 | KMT2A (0.51) | KMT2ANPC1ALDH1A1MEN1RAB9A | |
| SCHEMBL23315583 | 0.83 | NPC1 (0.62) | KMT2ANPC1PTGDR2ALOX15 | |
| SCHEMBL23315504 | 0.78 | AGTR2 (0.60) | — | |
| SCHEMBL23315202 | 0.78 | AGTR2 (0.42) | KMT2AALDH1A1MEN1S1PR1GAA | |
| SCHEMBL23315327 | 0.78 | AGTR2 (0.42) | KMT2AALDH1A1MEN1S1PR1GAA | |
| SCHEMBL17607347 | 0.75 | ACACB (0.49) | KMT2ANPC1 | |
| SCHEMBL5132181 | 0.73 | AGTR2 (0.68) | KMT2ANPC1MEN1PTGDR2 | |
| SCHEMBL11747939 | 0.72 | AGTR2 (0.53) | KMT2ANPC1 | |
| SCHEMBL29569463 | 0.71 | NPC1 (0.78) | KMT2ANPC1ALDH1A1MEN1RAB9A | |
| SCHEMBL25605335 | 0.71 | NPC1 (0.78) | KMT2ANPC1ALDH1A1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3620454-B1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |