Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 7/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23318455 | 0.80 | MTNR1B (0.37) | MEN1KMT2ASMN1; SMN2FAAHMTNR1B | |
| SCHEMBL21561029 | 0.74 | RXFP1 (0.37) | LIPEMEN1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL21561127 | 0.73 | FAAH (0.40) | MEN1KMT2ASMN1; SMN2FAAHALDH1A1 | |
| SCHEMBL24489623 | 0.73 | FAAH (0.36) | MEN1KMT2AHSD17B10SMN1; SMN2FAAH | |
| SCHEMBL21023276 | 0.72 | RXFP1 (0.36) | LIPEMEN1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL20808479 | 0.71 | RXFP1 (0.35) | LIPEMEN1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL21948654 | 0.71 | FAAH (0.35) | MEN1KMT2AHSD17B10SMN1; SMN2FAAH | |
| SCHEMBL9591943 | 0.69 | POLB (0.51) | LIPEMEN1KMT2ASMN1; SMN2FAAH | |
| SCHEMBL11022210 | 0.68 | GAA (0.65) | MEN1KMT2AHSD17B10SMN1; SMN2MTNR1A | |
| SCHEMBL20694601 | 0.67 | ACACB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087096-A1 | P53 MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-05-06 | — | — | WO | disclosed |