Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320083 | 0.78 | ADRB2 (0.34) | ADRB2ADRB1 | |
| SCHEMBL23320013 | 0.78 | ADRB2 (0.34) | ADRB2ADRB1 | |
| SCHEMBL23319806 | 0.77 | ADRB2 (0.34) | ADRB2ADRB1 | |
| SCHEMBL29909992 | 0.76 | ADRB2 (0.31) | ADRB2ADRB1 | |
| SCHEMBL20698784 | 0.76 | ADRB2 (0.31) | ADRB2ADRB1 | |
| SCHEMBL20681063 | 0.70 | — | — | |
| SCHEMBL23320084 | 0.70 | ADRB2 (0.39) | ADRB2ADRB1TSHR | |
| SCHEMBL22282345 | 0.69 | — | — | |
| SCHEMBL29910052 | 0.67 | ALDH1A1 (0.42) | ADRB2ADRB1TSHR | |
| SCHEMBL23320025 | 0.66 | MAPK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267276-A1 | NLRP MODULATORS | NOVARTIS INFLAMMASOME RESEARCH, INC. | 2022-08-25 | — | — | US | disclosed |
| EP-3817817-A1 | NLRP MODULATORS | Novartis AG (CH) | 2021-05-12 | — | — | EP | disclosed |
| CN-112584899-A | NLRP modulators | 诺华股份有限公司 | 2021-03-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267276-A1 | NLRP MODULATORS | NLRP1, NRP1, NR4A3 | ADRB2 244/4885ADRB1 142/4885TSHR 2357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.