Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344883 | 0.77 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10USP2ALOX15 | |
| SCHEMBL20098041 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10USP2ALOX15 | |
| SCHEMBL21432120 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10USP2ALOX15 | |
| SCHEMBL22166132 | 0.71 | PGR (0.37) | ALDH1A1HPGDHSD17B10USP2ALOX15 | |
| SCHEMBL23320084 | 0.71 | ADRB2 (0.39) | ALDH1A1HPGDHSD17B10USP2ALOX15 | |
| SCHEMBL23320013 | 0.71 | ADRB2 (0.34) | ADRB2ADRB1 | |
| SCHEMBL23320083 | 0.71 | ADRB2 (0.34) | ADRB2ADRB1 | |
| SCHEMBL18552783 | 0.70 | ALDH1A1 (0.46) | ALDH1A1HPGDHSD17B10USP2ALOX15 | |
| SCHEMBL2632858 | 0.70 | TRPV4 (0.46) | ALDH1A1HPGDHSD17B10USP2ALOX15 | |
| SCHEMBL20242375 | 0.70 | KHK (0.35) | ALDH1A1HPGDHSD17B10USP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267276-A1 | NLRP MODULATORS | NOVARTIS INFLAMMASOME RESEARCH, INC. | 2022-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267276-A1 | NLRP MODULATORS | NLRP1, NRP1, NR4A3 | ALDH1A1 2512/4885HPGD 2768/4885HSD17B10 2044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.