Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.56 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.56 |
| ▸ | GRM5 | P41594 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL27775256 | 1.00 | SMARCA2 (0.56) | SMARCA2SMARCA4GRM5HDAC4AR | |
| Trifluoroacetic Acid SCHEMBL15620942 | 0.83 | SORT1 (0.51) | SMARCA2SMARCA4GRM5HDAC4 | |
| SCHEMBL9278345 | 0.77 | SMARCA2 (0.65) | SMARCA2SMARCA4GRM5HDAC4AR | |
| SCHEMBL1400789 | 0.75 | SMARCA2 (0.68) | SMARCA2SMARCA4GRM5HDAC4AR | |
| Phenylguanidine SCHEMBL7425328 | 0.74 | CHIT1 (0.49) | HDAC4KLK1KLK5ALDH1A1RAB9A | |
| SCHEMBL9599834 | 0.73 | SMARCA2 (0.86) | SMARCA2SMARCA4ALDH1A1RAB9AMAPT | |
| SCHEMBL22125245 | 0.71 | SMARCA2 (1.00) | SMARCA2SMARCA4HDAC4 | |
| SCHEMBL5145795 | 0.71 | SMARCA2 (0.65) | SMARCA2SMARCA4ARJAK2TYK2 | |
| SCHEMBL31434913 | 0.71 | SMARCA2 (0.66) | SMARCA2SMARCA4GRM5JAK2TYK2 | |
| SCHEMBL26922946 | 0.71 | SMARCA2 (0.57) | SMARCA2SMARCA4GRM5HDAC4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273759-B2 | Fungicide heterocyclyl-pyrimidinyl-amino derivatives | BAYER CROPSCIENCE AG (DE) | 2012-09-25 | — | — | US | disclosed |
| US-20110218188-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-09-08 | — | — | US | disclosed |
| EP-2356107-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-17 | — | — | EP | disclosed |
| US-20100204229-A1 | FUNGICIDE HETEROCYCLYL-PYRIMIDINYL-AMINO DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-08-12 | — | — | US | disclosed |
| WO-2010055077-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | disclosed |
| EP-2164841-A1 | FUNGICIDE HETEROCYCLYL-PYRIMIDINYL-AMINO DERIVATIVES | Bayer CropScience SA (FR) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008148889-A1 | FUNGICIDE HETEROCYCLYL-PYRIMIDINYL-AMINO DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218188-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP1A2, PNPO | SMARCA2 3430/4885SMARCA4 3101/4885GRM5 2422/4885 |
| US-20100204229-A1 | FUNGICIDE HETEROCYCLYL-PYRIMIDINYL-AMINO DERIVATIVES | PAH, CYP4X1, PRXL2A | SMARCA2 3247/4885SMARCA4 2956/4885GRM5 2376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.