Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195565 | 1.00 | CTSS (0.41) | CTSSCTSKNR1H2AAK1ANPEP | |
| SCHEMBL26805423 | 0.93 | CTSK (0.40) | CTSSCTSKAAK1ANPEPSLC1A3 | |
| SCHEMBL28764792 | 0.93 | CTSK (0.43) | CTSSCTSKAAK1SLC1A3SLC1A2 | |
| SCHEMBL20244849 | 0.91 | CTSK (0.45) | CTSSCTSKSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL22090642 | 0.91 | CTSK (0.45) | CTSSCTSKSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL19376814 | 0.91 | CTSS (0.36) | CTSSCTSKNR1H2AAK1ANPEP | |
| SCHEMBL17643592 | 0.91 | CTSS (0.36) | CTSSCTSKNR1H2AAK1ANPEP | |
| SCHEMBL486372 | 0.89 | CPN1 (0.41) | CTSSCTSKNR1H2AAK1ANPEP | |
| SCHEMBL18481441 | 0.87 | LMNA (0.37) | CTSSCTSKAAK1NOS1NOS3 | |
| Hydrochloric Acid SCHEMBL20235918 | 0.86 | LMNA (0.36) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |
| US-20220389005-A1 | 7,8-DIHYDROBENZO[E]PYRIDO[3,4-C]AZOCINE-2,5(3H,6H)-DIONE DERIVATIVES USEFUL AS A FACTOR XIA INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-12-08 | — | — | US | disclosed |
| WO-2021083328-A1 | POLYSUBSTITUTED ISOINDOLINE COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 中国科学院上海药物研究所 | 2021-05-06 | — | — | WO | disclosed |
| CN-1227248-C | Imidazolidine derivatives, their preparation, and their use as antinflamatory agent | AVENTIS PHARMA GMBH (DE) | 2005-11-16 | — | — | CN | disclosed |
| CN-1496360-A | Imidazolidine derivatives, their preparation, and their use as antinflamatory agent | ������ҽҩ�¹�����˾ | 2004-05-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220389005-A1 | 7,8-DIHYDROBENZO[E]PYRIDO[3,4-C]AZOCINE-2,5(3H,6H)-DIONE DERIVATIVES USEFUL AS A FACTOR XIA INHIBITORS | F2, F13B, SERPINE1 | CTSS 1445/4885CTSK 466/4885NR1H2 1979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.