SCHEMBL486372

SCHEMBL486372

CC(C)(C)OC(=O)C(N)CC1CCNCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 1/20 0.41
CPB2 Q96IY4 1/20 0.41
ANPEP P15144 1/20 0.38
ERAP2 Q6P179 1/20 0.38
CTSS P25774 2/20 0.35
CTSK P43235 2/20 0.35
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
NR1H2 P55055 1/20 0.32
ALOX15 P16050 1/20 0.32
SLC6A1 P30531 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRB2 P47870 2/20 0.32
SLC6A12 P48065 2/20 0.32
SLC6A11 P48066 2/20 0.32
SLC6A13 Q9NSD5 2/20 0.32
GABRA1 P14867 1/20 0.32
GABRR1 P24046 1/20 0.32
GABRA4 P48169 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27438518 0.91 SLC6A1 (0.40) CPN1CPB2ANPEPERAP2CTSS
SCHEMBL23325684 0.89 CTSS (0.41) ANPEPCTSSCTSKNR1H2NOS1
SCHEMBL5195565 0.89 CTSS (0.41) ANPEPCTSSCTSKNR1H2NOS1
SCHEMBL7358207 0.88 CPN1 (0.37) CPN1CPB2ANPEPERAP2CTSS
SCHEMBL28764792 0.85 CTSK (0.43) CTSSCTSKAAK1
SCHEMBL26805423 0.85 CTSK (0.40) ANPEPCTSSCTSKAAK1
SCHEMBL20244849 0.84 CTSK (0.45) CTSSCTSK
SCHEMBL22090642 0.84 CTSK (0.45) CTSSCTSK
SCHEMBL27540688 0.84 CTSS (0.33) CTSSCTSKNR1H2NOS1NOS3
SCHEMBL6630066 0.83 CPN1 (0.41) CPN1CPB2ANPEPERAP2CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087442-A1 AMINO-IMIDAZOLE ANTIBACTERIAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed
EP-4719381-A1 LIGAND-POLAR DRUG CONJUGATES Tripartite Therapeutics Inc. (TW) 2026-04-08 EP disclosed
US-12569566-B2 Compositions containing, methods and uses of antibody-TLR agonist conjugates AMBRX, INC. (US) 2026-03-10 US disclosed
CN-121574171-A Difunctional protein degradation agent of direct targeting proteasome, preparation method and application thereof 浙大城市学院 2026-02-27 CN disclosed
EP-4161931-B1 NOVEL IMIDAZOPYRAZINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2026-02-18 EP disclosed
CN-119455003-A Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2025-02-18 CN disclosed
CN-119455004-A Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2025-02-18 CN disclosed
US-20250032635-A1 LIGAND-POLAR DRUG CONJUGATES TRIPARTITE THERAPEUTICS INC. (TW) 2025-01-30 US disclosed
CN-119371403-A Azaaromatic ring carboxamide compound and application thereof 广州国家实验室 2025-01-28 CN disclosed
CN-119233974-A Indolone derivative and application thereof 康百达(四川)生物医药科技有限公司 2024-12-31 CN disclosed
US-20070055065-A1 N-sulphonylated amino acid derivatives, method for the production and use thereof CURACYTE CHEMISTRY GMBH (DE) 2007-03-08 US disclosed
CN-1880317-A Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors SCHERING CORP (US) 2006-12-20 CN disclosed
CN-1266118-C Novel delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides NOVARTIS AG (CH) 2006-07-26 CN disclosed
EP-1651597-A2 N-SULPHONYLATED AMINO ACID DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF Curacyte Chemistry GmbH (DE) 2006-05-03 EP disclosed
CN-1735614-A Pyrazolopyrimidines as cyclin dependent kinase inhibitors SCHERING CORP (US) 2006-02-15 CN disclosed
CN-1550491-A Novel delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides ��˹��ŵ�� 2004-12-01 CN disclosed
WO-2004101507-A2 N-SULPHONYLATED AMINO ACID DERIVATIVES AND USE THEREOF AS MATRIPTASE INHIBITORS CURACYTE CHEMISTRY GMBH (DE) 2004-11-25 WO disclosed
CN-1153759-C Novel delta-amino-gamma hydroxy-omega-aryl-alkanamides ��˹��ŵ�� 2004-06-16 CN disclosed
EP-0701568-A1 NEW PEPTIDE DERIVATIVES Astra Aktiebolag (SE) 1996-03-20 EP disclosed
CN-1117960-A Novel delta-amino-gamma hydroxy-omega-aryl-alkanamides CIBA GEIGY AG (CH) 1996-03-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070055065-A1 N-sulphonylated amino acid derivatives, method for the production and use thereof DNPEP, ANPEP, PEPD CPN1 88/4885CPB2 583/4885ANPEP 2/4885
US-20250032635-A1 LIGAND-POLAR DRUG CONJUGATES CD274, SELPLG, PDCD1LG2 CPN1 3810/4885CPB2 1729/4885ANPEP 1478/4885
US-12569566-B2 Compositions containing, methods and uses of antibody-TLR agonist conjugates TLR3, TLR2, TLR1 CPN1 2022/4885CPB2 3459/4885ANPEP 612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.