SCHEMBL23327014

SCHEMBL23327014

Clc1cc(Br)cc(Br)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.41
CYP3A4 P08684 4/20 0.41
TDP1 Q9NUW8 1/20 0.41
NMT1 P30419 1/20 0.41
ALDH1A1 P00352 2/20 0.38
GABRA1 P14867 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRA2 P47869 1/20 0.36
GABRB2 P47870 1/20 0.36
HPGD P15428 5/20 0.35
HSD17B10 Q99714 5/20 0.35
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
CASP1 P29466 1/20 0.35
AHR P35869 6/20 0.35
AKR1B1 P15121 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MAPK1 P28482 1/20 0.32
GPR35 Q9HC97 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30007490 1.00 TSHR (0.41) TSHRCYP3A4TDP1NMT1ALDH1A1
SCHEMBL10872330 0.84 ALDH1A1 (0.53) TSHRCYP3A4TDP1NMT1ALDH1A1
SCHEMBL25259748 0.84 TDP1 (0.47) TSHRCYP3A4TDP1NMT1ALDH1A1
SCHEMBL29363465 0.78 RAPGEF4 (0.39) TSHRCYP3A4TDP1ALDH1A1HPGD
SCHEMBL3930536 0.78 RAPGEF4 (0.39) TSHRCYP3A4TDP1ALDH1A1HPGD
SCHEMBL22419005 0.78 CYP3A4 (0.32) CYP3A4NMT1ALDH1A1
SCHEMBL6500390 0.77 ALDH1A1 (0.61) TSHRCYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL30293826 0.77 ALDH1A1 (0.61) TSHRCYP3A4ALDH1A1HPGDHSD17B10
SCHEMBL28667897 0.77 TDP1 (0.41) TSHRCYP3A4TDP1NMT1GABRA1
SCHEMBL4448671 0.74 NMT1 (0.39) TSHRCYP3A4TDP1NMT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240251676-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-25 US disclosed
EP-4326731-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES Samsung Display Co., Ltd. (KR) 2024-02-28 EP disclosed
US-20240002410-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-04 US disclosed
CN-117242082-A Organic molecules for optoelectronic devices 三星显示有限公司 2023-12-15 CN disclosed
US-11785837-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-10 US disclosed
US-11785837-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-10 US disclosed
US-11785837-B2 Organic electroluminescence device and polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-10 US disclosed
US-20230189647-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-20230174558-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-08 US disclosed
US-20230167135-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-01 US disclosed
CN-115461350-A Organic molecules for optoelectronic devices 三星显示有限公司 2022-12-09 CN disclosed
CN-115443280-A Organic molecules for optoelectronic devices 三星显示有限公司 2022-12-06 CN disclosed
WO-2022223848-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2022-10-27 WO disclosed
CN-113875034-A Organic light emitting device 株式会社LG化学 2021-12-31 CN disclosed
WO-2021214308-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-10-28 WO disclosed
WO-2021214310-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-10-28 WO disclosed
WO-2021214306-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-10-28 WO disclosed
WO-2021214309-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-10-28 WO disclosed
US-20210143331-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-05-13 US disclosed
CN-112786816-A Organic electroluminescent device and polycyclic compound for organic electroluminescent device 三星显示有限公司 2021-05-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240002410-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES OR10J3, NR4A3, NR2E3 TSHR 1347/4885CYP3A4 290/4885TDP1 4638/4885
US-20240251676-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES NR2E3, ORC3, OR10J3 TSHR 384/4885CYP3A4 1131/4885TDP1 4726/4885
US-20230167135-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES OR10J3, NOX3, ORC3 TSHR 1402/4885CYP3A4 2437/4885TDP1 4694/4885
US-20230174558-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES OR10J3, OR51E2, C1S TSHR 3444/4885CYP3A4 501/4885TDP1 3365/4885
US-20230189647-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES OR10J3, ORC3, NR2E3 TSHR 1368/4885CYP3A4 1686/4885TDP1 4673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.