Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23329217 | 0.79 | GP6 (0.41) | MKNK1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL18004675 | 0.77 | CYP11B2 (0.55) | MKNK1MKNK2CYP2A6ALDH1A1CYP3A4 | |
| SCHEMBL29852332 | 0.75 | MKNK1 (0.56) | MKNK1MKNK2CYP2A6ALDH1A1CYP3A4 | |
| SCHEMBL23294594 | 0.75 | MKNK1 (0.56) | MKNK1MKNK2CYP2A6ALDH1A1CYP3A4 | |
| SCHEMBL29852180 | 0.75 | MKNK1 (0.56) | MKNK1MKNK2CYP2A6ALDH1A1CYP3A4 | |
| SCHEMBL23294359 | 0.75 | MKNK1 (0.56) | MKNK1MKNK2CYP2A6ALDH1A1CYP3A4 | |
| SCHEMBL23329267 | 0.73 | KDM4E (0.41) | CYP2A6ALDH1A1CYP1A2KDM4ELMNA | |
| SCHEMBL23328899 | 0.73 | ESR1 (0.45) | ALDH1A1CYP1A2CYP11B2HPGDCYP19A1 | |
| SCHEMBL6212482 | 0.72 | MKNK1 (1.00) | MKNK1MKNK2CYP2A6ALDH1A1CYP3A4 | |
| SCHEMBL30462079 | 0.72 | MKNK1 (1.00) | MKNK1MKNK2CYP2A6ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11806335-B2 | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | Lilac Therapeutics, Inc. (US) | 2023-11-07 | — | — | US | disclosed |
| US-20210128532-A1 | HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS | Lilac Therapeutics, Inc. | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11806335-B2 | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | UGDH, PGD, PNPO | MKNK1 3973/4885MKNK2 3939/4885CYP2A6 599/4885 |
| US-20210128532-A1 | HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS | UGDH, PGD, PNPO | MKNK1 3973/4885MKNK2 3939/4885CYP2A6 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.