Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23329316 | 0.87 | MTNR1B (0.46) | MTNR1AMTNR1BALDH1A1LMNAOPRM1 | |
| SCHEMBL23329761 | 0.81 | GRIN1 (0.41) | LMNAOPRM1OPRK1MEN1KMT2A | |
| SCHEMBL18174911 | 0.77 | GRIN1 (0.47) | LMNAOPRM1OPRK1MEN1KMT2A | |
| SCHEMBL22945773 | 0.75 | GRIN1 (0.46) | LMNAOPRM1OPRK1MEN1KMT2A | |
| SCHEMBL23329596 | 0.74 | GRIN1 (0.36) | ALDH1A1LMNAOPRM1OPRK1MEN1 | |
| SCHEMBL23329320 | 0.73 | OPRM1 (0.58) | LMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL23072577 | 0.73 | GRIN1 (0.43) | LMNAOPRM1OPRK1MEN1KMT2A | |
| SCHEMBL23329630 | 0.73 | OPRM1 (0.37) | LMNAOPRM1HTTOPRD1OPRK1 | |
| SCHEMBL16015668 | 0.71 | GRIN1 (0.46) | LMNAOPRM1OPRK1MEN1KMT2A | |
| SCHEMBL25906877 | 0.71 | GRIN1 (0.43) | LMNAOPRM1OPRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130316-A1 | MORPHINAN DERIVATIVES AND COMPOSITIONS COMPRISING THE SAME FOR TREATING AUTOIMMUNE, INFLAMMATION OR INFECTION RELATED DISORDERS | TAIWANJ PHARMACEUTICALS CO., LTD (TW) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130316-A1 | MORPHINAN DERIVATIVES AND COMPOSITIONS COMPRISING THE SAME FOR TREATING AUTOIMMUNE, INFLAMMATION OR INFECTION RELATED DISORDERS | TLR4, TLR1, TLR3 | MTNR1A 301/4885MTNR1B 161/4885ALDH1A1 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.