Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.60 |
| ▸ | CCR3 | P51677 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4237889 | 0.85 | OPRK1 (0.65) | HRH1CCR3KCNH2ADRB2MEN1 | |
| SCHEMBL23304422 | 0.82 | HRH1 (0.60) | HRH1CCR3KCNH2ADRB2MEN1 | |
| SCHEMBL7179272 | 0.79 | MEN1 (0.68) | MEN1KMT2ALTA4H | |
| SCHEMBL27805654 | 0.77 | LTA4H (0.62) | MEN1KMT2AHRH3LTA4H | |
| SCHEMBL25933641 | 0.76 | HRH3 (0.61) | HRH1CCR3KCNH2ADRB2MEN1 | |
| SCHEMBL2276951 | 0.76 | HRH1 (0.55) | HRH1CCR3KCNH2ADRB2MEN1 | |
| SCHEMBL3022521 | 0.76 | OPRK1 (0.76) | KCNH2ADRB2MEN1KMT2AHRH3 | |
| Hydrochloric Acid SCHEMBL6538607 | 0.75 | HTR2A (0.55) | KMT2AHRH3LTA4H | |
| SCHEMBL23632055 | 0.75 | ADRB2 (0.66) | HRH1CCR3KCNH2ADRB2MEN1 | |
| SCHEMBL23632053 | 0.75 | ADRB2 (0.66) | HRH1CCR3KCNH2ADRB2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021086879-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2021-05-06 | — | — | WO | disclosed |