Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 6/20 | 0.40 |
| ▸ | FPR3 | P25089 | 4/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23329451 | 0.87 | RORC (0.43) | RORCJAK2JAK1FPR2FPR3 | |
| SCHEMBL23329718 | 0.79 | AOC2 (0.54) | RORCGPR119 | |
| SCHEMBL4975040 | 0.75 | GPR119 (0.51) | GPR119TACR1ALDH1A1LMNAMAPT | |
| SCHEMBL16764525 | 0.74 | RORC (0.53) | RORCJAK2JAK1FPR2FPR3 | |
| SCHEMBL5453826 | 0.74 | GPR119 (0.51) | FPR2FPR3GPR119ALDH1A1MAPT | |
| SCHEMBL23536352 | 0.74 | USP2 (0.46) | TACR1ALDH1A1LMNAMAPT | |
| SCHEMBL19336744 | 0.74 | GPR119 (0.46) | GPR119TACR1MEN1KMT2AALDH1A1 | |
| SCHEMBL26246633 | 0.72 | RORC (0.46) | RORCJAK2JAK1FPR2FPR3 | |
| SCHEMBL18321714 | 0.72 | RORC (0.46) | RORCJAK2JAK1FPR2FPR3 | |
| SCHEMBL1199600 | 0.72 | RORC (0.51) | RORCJAK2JAK1FPR2FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021083209-A1 | SSAO INHIBITORS AND USE THEREOF | ECCOGENE (SHANGHAI) CO., LTD. (CN) | 2021-05-06 | — | — | WO | disclosed |