SCHEMBL23330850

SCHEMBL23330850

FC1(F)CCN(c2cnc(Cl)nc2Cl)C1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 13/20 0.39
CNR1 P21554 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
F2RL1 P55085 1/20 0.34
TNNI3K Q59H18 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
MAPT P10636 1/20 0.33
MAP3K12 Q12852 1/20 0.32
PDE10A Q9Y233 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23330855 0.81 CNR2 (0.36) CNR2CNR1SMN1; SMN2F2RL1TNNI3K
SCHEMBL17269955 0.74 POLB (0.40) CNR2SMN1; SMN2MAPT
SCHEMBL30135454 0.74 CNR2 (0.51) CNR2CNR1SMN1; SMN2PDE10A
SCHEMBL24393197 0.73 ALDH1A1 (0.41) CNR2SMN1; SMN2
SCHEMBL23330854 0.72 CNR2 (0.38) CNR2CNR1F2RL1MAP3K12PDE10A
SCHEMBL26711595 0.72 TRPV1 (0.42) CNR2HRH3MAP3K12PDE10A
SCHEMBL29224929 0.72 HRH3 (0.34) CNR2CNR1SMN1; SMN2HRH3MAPT
SCHEMBL30463633 0.72 HRH3 (0.34) CNR2CNR1SMN1; SMN2HRH3MAPT
SCHEMBL27144457 0.72 PDCD1 (0.41) CNR2CNR1PDE10A
SCHEMBL3767624 0.70 MAPK1 (0.42) CNR2SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230028221-A1 EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF JING MEDICINE TECHNOLOGY (SHANGHAI) LTD. (CN) 2023-01-26 US disclosed
WO-2021083380-A1 EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海科技大学 2021-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230028221-A1 EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF CYP4F11, CYP4A11, HSD11B1 CNR2 3520/4885CNR1 2983/4885SMN1; SMN2 4572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.