Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | LAP3 | P28838 | 1/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23306460 | 1.00 | LTA4H (0.47) | LTA4HLAP3SLC15A1ABCB1LNPEP | |
| Trifluoroacetic Acid SCHEMBL30098486 | 0.95 | LTA4H (0.43) | LTA4HLAP3SLC15A1ABCB1LNPEP | |
| Trifluoroacetic Acid SCHEMBL28836301 | 0.95 | LTA4H (0.43) | LTA4HLAP3SLC15A1ABCB1LNPEP | |
| SCHEMBL23306466 | 0.91 | LTA4H (0.47) | LTA4HLAP3SLC15A1ABCB1LNPEP | |
| SCHEMBL23332190 | 0.91 | LTA4H (0.47) | LTA4HLAP3SLC15A1ABCB1LNPEP | |
| Trifluoroacetic Acid SCHEMBL30098504 | 0.87 | LTA4H (0.43) | LTA4HLAP3SLC15A1ABCB1LNPEP | |
| Trifluoroacetic Acid SCHEMBL28836548 | 0.87 | LTA4H (0.43) | LTA4HLAP3SLC15A1ABCB1LNPEP | |
| SCHEMBL23332011 | 0.84 | TACR1 (0.46) | LTA4HLAP3ABCB1MAOB | |
| SCHEMBL24942191 | 0.81 | LTA4H (0.55) | LTA4HLAP3SLC15A1SLC7A5ALDH1A1 | |
| SCHEMBL23306289 | 0.80 | REN (0.48) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230028516-A1 | PRODRUGS OF ITACONATE AND METHYL ITACONATE | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR V.V.I. (CZ) | 2023-01-26 | — | — | US | disclosed |
| WO-2021087082-A1 | PRODRUGS OF ITACONATE AND METHYL ITACONATE | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230028516-A1 | PRODRUGS OF ITACONATE AND METHYL ITACONATE | HADHA, IMPDH1, CYP27A1 | LTA4H 543/4885LAP3 2161/4885SLC15A1 767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.