Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24969581 | 0.88 | ALDH1A1 (0.48) | TGM2ALDH1A1TSHRCTSKITGB3 | |
| SCHEMBL30684686 | 0.85 | MGLL (0.58) | TGM2ALDH1A1TSHRCTSKITGB3 | |
| SCHEMBL3445777 | 0.82 | MEN1 (0.65) | TGM2ALDH1A1TSHRCTSKCTSS | |
| SCHEMBL10241524 | 0.82 | MEN1 (0.65) | TGM2ALDH1A1TSHRCTSKCTSS | |
| SCHEMBL391537 | 0.82 | MEN1 (0.65) | TGM2ALDH1A1TSHRCTSKCTSS | |
| SCHEMBL21702752 | 0.81 | MEN1 (0.63) | ALDH1A1TSHRCTSKCTSSFOLH1 | |
| Hydrochloric Acid SCHEMBL28881882 | 0.81 | MEN1 (0.63) | TGM2ALDH1A1TSHRCTSKCTSS | |
| Hydrochloric Acid SCHEMBL28881885 | 0.81 | MEN1 (0.63) | TGM2ALDH1A1TSHRCTSKCTSS | |
| SCHEMBL5007433 | 0.79 | CTSK (0.57) | TGM2ALDH1A1TSHRCTSKCTSS | |
| SCHEMBL5007432 | 0.79 | CTSK (0.57) | TGM2ALDH1A1TSHRCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130395-A1 | PROXIMITY INDUCED SITE-SPECIFIC ANTIBODY CONJUGATION | WILLIAM MARSH RICE UNIVERSITY (US) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130395-A1 | PROXIMITY INDUCED SITE-SPECIFIC ANTIBODY CONJUGATION | CD2BP2, FCGR2A, FCGR3B | TGM2 985/4885ALDH1A1 3643/4885TSHR 1513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.