Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.38 |
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | CA6 | P23280 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779770 | 0.77 | ALDH1A1 (0.36) | TDP1 | |
| SCHEMBL7558100 | 0.77 | NAPRT (0.33) | TSHR | |
| SCHEMBL15174829 | 0.74 | PSIP1 (0.35) | — | |
| SCHEMBL1076498 | 0.73 | GOT1 (0.40) | CA2CA12CA9CA1CA14 | |
| SCHEMBL8613791 | 0.72 | NPC1 (0.34) | TSHR | |
| SCHEMBL134192 | 0.71 | MEN1 (0.34) | — | |
| SCHEMBL27459398 | 0.71 | HTR6 (0.48) | CA2CA12CA9CA1CA14 | |
| SCHEMBL27802584 | 0.71 | — | — | |
| SCHEMBL29268543 | 0.70 | MEN1 (0.37) | — | |
| SCHEMBL27530084 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558496-A1 | NOVEL PYRIMIDINYL AND TRIAZINYL SULFONAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024017863-A1 | NOVEL PYRIMIDINYL AND TRIAZINYL SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-01-25 | — | — | WO | disclosed |
| WO-2024017863-A1 | NOVEL PYRIMIDINYL AND TRIAZINYL SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-01-25 | — | — | WO | disclosed |
| CN-102822150-B | 1,2, 4-triazin-4-amine derivatives | HEPTARES THERAPEUTICS LTD | 2014-12-03 | — | — | CN | disclosed |
| CN-104136439-A | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF | BAYER IP GMBH | 2014-11-05 | — | — | CN | disclosed |
| CN-103764657-A | Hydroxymethylaryl-substituted pyrrolotriazines as ALKL inhibitors | BAYER IP GMBH | 2014-04-30 | — | — | CN | disclosed |
| CN-102822150-A | 1,2, 4-triazin-4-amine derivatives | HEPTARES THERAPEUTICS LTD | 2012-12-12 | — | — | CN | disclosed |
| EP-2356101-A1 | PYRIMIDINE AND TRIAZINE SULFONAMIDE DERIVATES AS B1 BRADYKININ RECEPTOR (B1R) INHIBITORS FOR TREATING PAIN | Grünenthal GmbH (DE) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010046109-A1 | PYRIMIDINE AND TRIAZINE SULFONAMIDE DERIVATES AS B1 BRADYKININ RECEPTOR (B1R) INHIBITORS FOR TREATING PAIN | Grünenthal GmbH (DE) | 2010-04-29 | — | — | WO | disclosed |
| US-4756991-A | Pigmented resin particles coated with silicone oil and water soluble polymeric quaternary ammonium compound; nonelectroscopic | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-07-12 | — | — | US | disclosed |
| US-4501607-A | Herbicidal triazine sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
| US-4453970-A | Herbicidal triazinyl sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-12 | — | — | US | disclosed |
| US-4214890-A | PRE- AND POST-EMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-07-29 | — | — | US | disclosed |