⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665583 | 0.81 | CSF1R (0.34) | — | |
| SCHEMBL662340 | 0.78 | PRPS1 (0.39) | — | |
| SCHEMBL30361114 | 0.78 | PRPS1 (0.39) | — | |
| SCHEMBL2955159 | 0.78 | POLB (0.32) | — | |
| SCHEMBL5057753 | 0.78 | FDPS (0.39) | — | |
| SCHEMBL1668849 | 0.78 | CSF1R (0.38) | — | |
| SCHEMBL6950039 | 0.77 | FDPS (0.40) | — | |
| SCHEMBL661395 | 0.76 | LMNA (0.47) | — | |
| SCHEMBL661637 | 0.75 | HTT (0.45) | — | |
| SCHEMBL662697 | 0.75 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2533645-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | The Johns Hopkins University (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011100373-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-08-18 | — | — | WO | disclosed |