SCHEMBL23337076

SCHEMBL23337076

Cc1ccc2ccccc2c1N1C(=CC=C2C(=O)c3cc4ccccc4cc3C2=O)N(c2c(C)ccc3ccccc23)c2nc3ccccc3nc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR1 Q9BXC0 3/20 0.40
POLB P06746 1/20 0.32
HCRTR1 O43613 1/20 0.31
HCRTR2 O43614 1/20 0.31
CYP1A2 P05177 2/20 0.31
GAA P10253 2/20 0.31
TDO2 P48775 1/20 0.31
IDO2 Q6ZQW0 1/20 0.31
CYP2A6 P11509 1/20 0.31
TSHR P16473 1/20 0.31
MAPT P10636 2/20 0.30
KMT2A Q03164 2/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
ALDH1A1 P00352 3/20 0.30
DNMT1 P26358 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23338726 0.85 MAPT (0.33) TDO2IDO2MAPTKMT2ALMNA
SCHEMBL23337901 0.85 NQO2 (0.33) GAATDO2IDO2MAPTKMT2A
SCHEMBL25849608 0.82 ALDH1A1 (0.37) POLBMAPTKMT2ALMNAKDM4E
SCHEMBL23337854 0.81 POLB (0.43) HCAR1POLBTDO2IDO2MAPT
SCHEMBL23337905 0.81 KMT2A (0.40) HCAR1GAATSHRMAPTKMT2A
SCHEMBL25850367 0.81 MEN1 (0.33) POLBMAPTKMT2AMEN1ALDH1A1
SCHEMBL23338714 0.80 LMNA (0.34) TDO2IDO2MAPTKMT2ALMNA
SCHEMBL25849603 0.79 ILF3 (0.32) MAPTKMT2ALMNATP53KDM4E
SCHEMBL23337974 0.79 ALDH1A1 (0.40) CYP1A2TDO2IDO2TSHRMAPT
SCHEMBL23337591 0.79 DPP4 (0.39) CYP1A2TSHRMAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210135128-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2021-05-06 US disclosed