SCHEMBL25849608

SCHEMBL25849608

Cc1cccc(C)c1N1/C(=C/C=C2C(=O)c3cc4ccccc4cc3C2=O)N(C)c2nc3ccccc3nc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
POLB P06746 1/20 0.37
ATM Q13315 1/20 0.33
MAPT P10636 6/20 0.32
MAPK1 P28482 2/20 0.32
LMNA P02545 1/20 0.32
ILF3 Q12906 1/20 0.32
HPGD P15428 1/20 0.32
ANPEP P15144 2/20 0.32
DPP4 P27487 2/20 0.32
APEX1 P27695 1/20 0.32
RAB9A P51151 2/20 0.31
NFKB1 P19838 1/20 0.31
CASP3 P42574 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SENP8 Q96LD8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849603 0.92 ILF3 (0.32) ALDH1A1KMT2AMAPTLMNAILF3
SCHEMBL25849609 0.88 MAPK14 (0.33) ALDH1A1ILF3KDM4E
SCHEMBL25849611 0.88 PDE7A (0.32) ILF3
SCHEMBL25850367 0.88 MEN1 (0.33) ALDH1A1KMT2AMEN1POLBATM
SCHEMBL25849554 0.86 DPP4 (0.36) KMT2AMEN1MAPTILF3ANPEP
SCHEMBL25849612 0.86 ILF3 (0.39) ALDH1A1KMT2AMEN1MAPTLMNA
SCHEMBL23338726 0.85 MAPT (0.33) ALDH1A1KMT2AMEN1ATMMAPT
SCHEMBL25849601 0.85 ILF3 (0.34) ALDH1A1KMT2AMEN1MAPTMAPK1
SCHEMBL25849597 0.83 DPP4 (0.34) ALDH1A1ATMMAPTANPEPDPP4
SCHEMBL25849846 0.83 ELANE (0.41) ALDH1A1KMT2AMEN1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed