SCHEMBL23337971

SCHEMBL23337971

O=C1CC(=O)c2c(Cl)cc(Cl)cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
UCHL1 P09936 1/20 0.44
UCHL3 P15374 1/20 0.44
ECE1 P42892 1/20 0.44
MUS81 Q96NY9 1/20 0.44
CES1 P23141 2/20 0.41
DNMT1 P26358 1/20 0.41
ALDH1A1 P00352 5/20 0.38
HPGD P15428 1/20 0.36
AHR P35869 1/20 0.36
RECQL P46063 3/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.35
CYP3A4 P08684 1/20 0.35
S100A4 P26447 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5681748 0.74 CES1 (0.52) L3MBTL1KMT2AMEN1CES1DNMT1
SCHEMBL8052912 0.74 AHR (0.45) L3MBTL1KMT2AMEN1UCHL1UCHL3
SCHEMBL2821364 0.73 MAPT (0.52) KMT2AUCHL1UCHL3ECE1MUS81
SCHEMBL11601993 0.72 CES1 (0.50) L3MBTL1KMT2AMEN1CES1DNMT1
SCHEMBL7043743 0.72 MEN1 (0.36) L3MBTL1KMT2AMEN1CES1DNMT1
SCHEMBL5823309 0.71 S100A4 (0.56) L3MBTL1CES1HPGDAHRS100A4
SCHEMBL16357217 0.69 UCHL1 (0.52) KMT2AMEN1UCHL1UCHL3ECE1
SCHEMBL29844266 0.68 MEN1 (0.52) L3MBTL1KMT2AMEN1CES1DNMT1
SCHEMBL2256507 0.68 MEN1 (0.52) L3MBTL1KMT2AMEN1CES1DNMT1
SCHEMBL9245568 0.67 PPOX (0.56) L3MBTL1KMT2AMEN1CES1DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3823054-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM Corporation (JP) 2021-05-19 EP disclosed
US-20210135128-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2021-05-06 US disclosed