SCHEMBL8052912

SCHEMBL8052912

O=C1CC(=O)c2cc(Cl)c(Cl)cc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.45
MAPK1 P28482 1/20 0.45
CES1 P23141 1/20 0.39
UCHL1 P09936 1/20 0.39
UCHL3 P15374 1/20 0.39
ECE1 P42892 1/20 0.39
MUS81 Q96NY9 1/20 0.39
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
TSHR P16473 1/20 0.36
THPO P40225 1/20 0.36
GRIA1 P42261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14453945 0.81 ALDH1A1 (0.33) CES1UCHL1UCHL3ECE1MUS81
SCHEMBL14453946 0.75 ALDH1A1 (0.36) UCHL1UCHL3ECE1MUS81MEN1
SCHEMBL5823309 0.74 S100A4 (0.56) AHRCES1HPGDL3MBTL1METAP1
SCHEMBL23337971 0.74 L3MBTL1 (0.46) AHRCES1UCHL1UCHL3ECE1
SCHEMBL29484391 0.73 EGFR (0.35)
SCHEMBL31022304 0.72 CES1 (0.45) AHRMAPK1CES1HPGDL3MBTL1
SCHEMBL4321232 0.71 AHR (0.53) AHRMAPK1CES1MEN1KMT2A
SCHEMBL16357223 0.71 AHR (0.30) AHRMETAP1
SCHEMBL20907232 0.71 HTT (0.38) CES1MEN1KMT2AHPGDKDM4E
SCHEMBL30559769 0.71 GRM5 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1013259-A1 Dyeing composition for fibres containing 1,3-indanediones Wella Aktiengesellschaft (DE) 2000-06-28 EP claimed
EP-1010419-A2 Agent containing 1,3-indane dione and aromatic amines for dyeing fibers Wella Aktiengesellschaft (DE) 2000-06-21 EP claimed
CN-119192204-A Dimer type receptor material, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-12-27 CN disclosed
CN-118530252-A Optoelectronic device, electronic apparatus, electronic equipment, and organic compound used therefor 三星显示有限公司 2024-08-23 CN disclosed
CN-115466270-B Electron acceptor material based on dicyanoindenothiazole terminal and application thereof 浙江大学 2024-03-19 CN disclosed
CN-115466270-A Electronic acceptor material based on dicyano indenothiazole terminal and application thereof 浙江大学 2022-12-13 CN disclosed
EP-3470471-B1 METHINE DYES LANXESS DEUTSCHLAND GMBH (DE) 2022-12-07 EP disclosed
CN-112390813-B Non-fullerene electron acceptor material and organic photovoltaic cell 位速科技股份有限公司 2022-06-03 CN disclosed
US-20220149298-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES UBIQUITOUS ENERGY, INC. (US) 2022-05-12 US disclosed
US-20220140266-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES UBIQUITOUS ENERGY, INC. (US) 2022-05-05 US disclosed
US-20220135587-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES UBIQUITOUS ENERGY, INC. (US) 2022-05-05 US disclosed
WO-2018114965-A1 CLPX INHIBITORY COMPOUNDS FOR THE TREATMENT OF MULTI RESISTANT STAPHYLOCOCCUS AUREUS VIRULENCE AND FOR THE TREATMENT OF LEUKEMIA Technische Universität München (DE) 2018-06-28 WO disclosed
WO-2018114965-A1 CLPX INHIBITORY COMPOUNDS FOR THE TREATMENT OF MULTI RESISTANT STAPHYLOCOCCUS AUREUS VIRULENCE AND FOR THE TREATMENT OF LEUKEMIA Technische Universität München (DE) 2018-06-28 WO disclosed
US-20140374733-A1 PHOTOELECTRIC CONVERSION ELEMENT, METHOD FOR USING THE SAME, IMAGING DEVICE, PHOTOSENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
US-20140374733-A1 PHOTOELECTRIC CONVERSION ELEMENT, METHOD FOR USING THE SAME, IMAGING DEVICE, PHOTOSENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
EP-1013259-A1 Dyeing composition for fibres containing 1,3-indanediones Wella Aktiengesellschaft (DE) 2000-06-28 EP disclosed
EP-1010419-A2 Agent containing 1,3-indane dione and aromatic amines for dyeing fibers Wella Aktiengesellschaft (DE) 2000-06-21 EP disclosed
US-6063788-A TREATMRNT OF ARTHERIOSCLEROSIS BAYER AKTIENGESELLSCHAFT (DE) 2000-05-16 US disclosed
EP-0825185-A1 Pyridine fused to a bicyclic ring BAYER AG (DE) 1998-02-25 EP disclosed
US-5591848-A Spiroconjugated charge-transfer dyes for optical applications THE PENN STATE RESEARCH FOUNDATION (US) 1997-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220140266-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES VIM, ALDH1A2, ICAM1 AHR 609/4885MAPK1 4204/4885CES1 4747/4885
US-20220149298-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES VIM, ALDH1A2, ICAM1 AHR 609/4885MAPK1 4204/4885CES1 4747/4885
US-20220135587-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES VIM, ALDH1A2, ICAM1 AHR 609/4885MAPK1 4204/4885CES1 4747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.