Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.46 |
| ▸ | ME2 | P23368 | 1/20 | 0.44 |
| ▸ | ME1 | P48163 | 1/20 | 0.44 |
| ▸ | ME3 | Q16798 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334053 | 0.85 | ALOX5 (0.70) | ALOX5CA2CAMK2AFNTAFNTB | |
| SCHEMBL16772742 | 0.83 | ALOX5 (0.52) | ALOX5POLBCA2CAMK2AGAA | |
| SCHEMBL2344710 | 0.83 | LMNA (0.49) | ESR1ESR2ALOX5RIPK1POLB | |
| SCHEMBL2343977 | 0.81 | ALOX5 (0.57) | ALOX5RIPK1POLBAPEX1TDP1 | |
| SCHEMBL2341738 | 0.75 | LMNA (0.47) | RIPK1POLBSMN1; SMN2LMNAHTT | |
| SCHEMBL2339858 | 0.73 | PTPN1 (0.42) | ALOX5RIPK1POLBAPEX1TDP1 | |
| SCHEMBL3454798 | 0.72 | POLB (0.44) | ESR1ESR2POLBAPEX1TDP1 | |
| SCHEMBL5724883 | 0.72 | RAB9A (0.68) | ESR1ESR2POLBAPEX1TDP1 | |
| SCHEMBL14959151 | 0.71 | TDP1 (0.62) | POLBAPEX1TDP1SMN1; SMN2LMNA | |
| SCHEMBL2113535 | 0.69 | ESR1 (1.00) | ESR1ESR2SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9210928-B2 | Plant development control composition | SYNGENTA CROP PROTECTION, LLC (US) | 2015-12-15 | — | — | US | disclosed |
| US-20150150253-A1 | CROP ENHANCEMENT COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-06-04 | — | — | US | disclosed |
| WO-2013186040-A2 | CROP ENHANCEMENT COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-12-19 | — | — | WO | disclosed |
| US-20110301028-A1 | PLANT DEVELOPMENT CONTROL COMPOSITION | SYNGENTA CROP PROTECTION, LLC (US) | 2011-12-08 | — | — | US | disclosed |
| EP-2358197-A2 | PLANT DEVELOPMENT CONTROL COMPOSITION | Syngenta Participations AG (CH) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010055316-A2 | PLANT DEVELOPMENT CONTROL COMPOSITION | THE UNIVERSITY OF WARWICK (GB) | 2010-05-20 | — | — | WO | disclosed |
| WO-2010055310-A1 | HERBICIDAL COMPOSITIONS | THE UNIVERSITY OF WARWICK (GB) | 2010-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150150253-A1 | CROP ENHANCEMENT COMPOSITIONS | ACHE, DDT, BCHE | ESR1 3107/4885ESR2 3392/4885ALOX5 600/4885 |
| US-20110301028-A1 | PLANT DEVELOPMENT CONTROL COMPOSITION | MSL1, OXSR1, OSR1 | ESR1 3578/4885ESR2 2583/4885ALOX5 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.