Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 10/20 | 0.34 |
| ▸ | IDH2 | P48735 | 8/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815366 | 0.87 | CCR1 (0.44) | CCR1CCR8ALDH1A1MEN1KMT2A | |
| SCHEMBL28856145 | 0.83 | CCR1 (0.58) | CCR1CCR8ALDH1A1CYP3A4METAP2 | |
| SCHEMBL22051478 | 0.80 | CCR1 (0.39) | CCR1CCR8METAP2 | |
| SCHEMBL20390730 | 0.79 | NOS3 (0.48) | CCR1CCR8IDH1MEN1KMT2A | |
| SCHEMBL3327100 | 0.73 | KDM4E (0.49) | CCR1CCR8CYP1A2KMT2AMETAP2 | |
| SCHEMBL14722908 | 0.72 | CCR1 (0.73) | CCR1CCR8IDH1IDH2CYP3A4 | |
| SCHEMBL30077166 | 0.71 | KMT2A (0.42) | JAK2CCR1CCR8HTR3EHTR3B | |
| SCHEMBL15347711 | 0.71 | KMT2A (0.42) | JAK2CCR1CCR8HTR3EHTR3B | |
| SCHEMBL7507586 | 0.71 | MEN1 (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL30492599 | 0.71 | CYP3A4 (0.50) | JAK2CCR1CCR8HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10995091-B2 | CXCR4 receptor antagonists | PROXIMAGEN LLC (US) | 2021-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10995091-B2 | CXCR4 receptor antagonists | CXCR4, CXCR1, CXCR2 | JAK2 617/4885CCR1 16/4885CCR8 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.