SCHEMBL233425

SCHEMBL233425

Fc1ccc(N2CCNCC2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 6/20 0.63
HTR3E A5X5Y0 3/20 0.63
HTR3B O95264 3/20 0.63
HTR3A P46098 3/20 0.63
HTR3D Q70Z44 3/20 0.63
HTR3C Q8WXA8 3/20 0.63
SIGMAR1 Q99720 3/20 0.63
HTR7 P34969 3/20 0.61
HTR1A P08908 2/20 0.61
MAOB P27338 1/20 0.59
ALDH1A1 P00352 2/20 0.57
LMNA P02545 2/20 0.57
MAPT P10636 1/20 0.57
MAPK1 P28482 1/20 0.57
HTT P42858 1/20 0.57
GFER P55789 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
ADRB2 P07550 1/20 0.57
NCF1 P14598 1/20 0.57
PLD1 Q13393 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL894537 1.00 ADRB1 (0.63) ADRB1HTR3EHTR3BHTR3AHTR3D
Bromide SCHEMBL10674981 0.98 ADRB1 (0.61) ADRB1HTR3EHTR3BHTR3AHTR3D
Hydrochloric Acid SCHEMBL1005870 0.98 ADRB1 (0.61) ADRB1HTR3EHTR3BHTR3AHTR3D
Hydrochloric Acid SCHEMBL714521 0.98 ADRB1 (0.61) ADRB1HTR3EHTR3BHTR3AHTR3D
Piperazine SCHEMBL7486912 0.98 ADRB1 (0.61) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL943026 0.94 HTR7 (0.70) ADRB1HTR3EHTR3BHTR3AHTR3D
Hydrochloric Acid SCHEMBL943219 0.92 HTR7 (0.68) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL5237662 0.92 HTR3A (0.57) ADRB1HTR3EHTR3BHTR3AHTR3D
Hydrochloric Acid SCHEMBL20141332 0.90 HTR3A (0.56) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL19597620 0.89 LTA4H (0.72) ADRB1HTR3EHTR3BHTR3AHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2905 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
US-12404243-B2 Inhibitors of the Wnt/beta-catenin pathway THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-09-02 US claimed
CN-120142518-A Method for detecting dinotefuran and tilmicosin in wetland system 重庆大学 2025-06-13 CN claimed
CN-119780305-A Method for analyzing and detecting related substances of desloratadine 浙江东亚药业股份有限公司 2025-04-08 CN claimed
CN-119684233-A Thickened oil viscosity reducer and preparation method and application thereof 胜利油田华滨化工有限责任公司 2025-03-25 CN claimed
CN-119574741-A Method for rapidly detecting catecholamine and metabolite content in blood 瑞莱谱(杭州)医疗科技有限公司 2025-03-07 CN claimed
CN-116660421-B Method for dividing brain fatigue degree of healthy personnel in industrial production based on column chromatography 中国民用航空总局第二研究所 2024-09-13 CN claimed
EP-4387826-A1 METHODS OF MAKING OMNIPHOBIC MATERIALS WITH HIERARCHICAL STRUCTURES AND USES THEREOF McMaster University (CA) 2024-06-26 EP claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO claimed
EP-0445811-B1 Nitrogen-containing heterocyclic compounds, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-06-14 EP claimed
EP-0341066-B1 Immunostimulating guanine derivatives, compositions and methods SCRIPPS CLINIC RES (US) 1994-11-09 EP claimed
US-5284661-A 4-Oxo-7-(biphenyl-4-yl)thieno(2,3-b)pyridines as antagonist of angiotensin II; hypertensive agents, cardiovascular disorders and strokes TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-02-08 US claimed
EP-0539180-A1 Antiviral agents SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1993-04-28 EP claimed
EP-0266549-B1 CINNAMYL AMINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1991-06-19 EP claimed
EP-0341066-A2 Immunostimulating guanine derivatives, compositions and methods SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1989-11-08 EP claimed
EP-0282050-A1 Carbonyl- and sulphonyl- derivatives of 2-(aminoalkylthio)- methyl-1,4-dihydropyridines, a method for their preparation and pharmaceutical compositions containing them BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1988-09-14 EP claimed
EP-0266549-A1 Cinnamyl amines, process for their preparation and pharmaceutical compositions containing them BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1988-05-11 EP claimed
US-4521534-A Imidazo[2,1-a]pyrrolo[2,1-c][1,4]benzodiazepine derivatives, methods of preparation and use AYERST, MCKENNA & HARRISON, LTD. (CA) 1985-06-04 US claimed
EP-0091511-A2 1-(3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl)-4-(substituted)-piperazines and -piperidines, a process for the preparation thereof, pharmaceutical compositions containing the same and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1983-10-19 EP claimed