SCHEMBL23344000

SCHEMBL23344000

N#Cc1c(-n2c3ccccc3c3ccccc32)c(-n2c3ccc(-c4ccncc4)cc3c3cc(-c4ccncc4)ccc32)c(-c2ccccc2)c(-n2c3ccc(-c4ccncc4)cc3c3cc(-c4ccncc4)ccc32)c1-n1c2ccccc2c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 3/20 0.39
SQOR Q9Y6N5 1/20 0.39
ADORA1 P30542 2/20 0.38
MKNK1 Q9BUB5 1/20 0.38
ADORA2A P29274 1/20 0.38
PIK3CA P42336 1/20 0.37
CYP11B2 P19099 1/20 0.37
NRP1 O14786 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
PRKACA P17612 1/20 0.36
CDK8 P49336 1/20 0.36
CLK2 P49760 1/20 0.36
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
CDK9 P50750 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31273005 0.98 MAPK14 (0.38) MAPK14SQORADORA1MKNK1ADORA2A
SCHEMBL23344062 0.98 MAPK14 (0.41) MAPK14SQORADORA1MKNK1ADORA2A
SCHEMBL31273268 0.94 MAPK14 (0.39) MAPK14SQORADORA1MKNK1ADORA2A
SCHEMBL31272450 0.94 MAPK14 (0.39) MAPK14SQORADORA1MKNK1ADORA2A
SCHEMBL23979223 0.94 SQOR (0.41) MAPK14SQORADORA1MKNK1ADORA2A
SCHEMBL22251505 0.93 PDE9A (0.39) KDM4EALDH1A1LMNANPSR1RXFP1
SCHEMBL20596032 0.93 PDE9A (0.39) KDM4EALDH1A1LMNANPSR1RXFP1
SCHEMBL21765780 0.93 PDE9A (0.39) KDM4EALDH1A1LMNANPSR1RXFP1
SCHEMBL20596020 0.93 PDE9A (0.39) KDM4EALDH1A1LMNANPSR1RXFP1
SCHEMBL22250955 0.93 PDE9A (0.39) KDM4EALDH1A1LMNANPSR1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210143342-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AROMATIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210143342-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AROMATIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE CTCF, LEF1, BRD4 MAPK14 1536/4885SQOR 396/4885ADORA1 2398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.