SCHEMBL23979223

SCHEMBL23979223

N#Cc1c(-n2c3ccccc3c3cc(-c4ccncc4)ccc32)c(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)c(-n2c3ccccc3c3cc(-c4ccncc4)ccc32)c(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)c1-n1c2ccccc2c2cc(-c3ccncc3)ccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SQOR Q9Y6N5 1/20 0.41
ADORA1 P30542 2/20 0.40
MKNK1 Q9BUB5 1/20 0.40
ADORA2A P29274 1/20 0.40
PIK3CA P42336 1/20 0.39
CYP11B2 P19099 1/20 0.39
PRKACA P17612 1/20 0.38
CDK8 P49336 1/20 0.38
CLK2 P49760 1/20 0.38
GSK3A P49840 1/20 0.38
GSK3B P49841 1/20 0.38
CDK9 P50750 1/20 0.38
CDK5 Q00535 1/20 0.38
PRKCQ Q04759 1/20 0.38
ROCK1 Q13464 1/20 0.38
DYRK1A Q13627 1/20 0.38
LRRK2 Q5S007 1/20 0.38
CLK4 Q9HAZ1 1/20 0.38
DYRK1B Q9Y463 1/20 0.38
NOTUM Q6P988 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23344042 0.97 MAPK14 (0.38) SQORADORA1MKNK1ADORA2APIK3CA
SCHEMBL31273005 0.94 MAPK14 (0.38) SQORADORA1MKNK1ADORA2APIK3CA
SCHEMBL23344000 0.94 MAPK14 (0.39) SQORADORA1MKNK1ADORA2APIK3CA
SCHEMBL31273268 0.93 MAPK14 (0.39) SQORADORA1MKNK1ADORA2APIK3CA
SCHEMBL31272450 0.93 MAPK14 (0.39) SQORADORA1MKNK1ADORA2APIK3CA
SCHEMBL23979224 0.92 TSPO (0.40) ADORA1CYP11B2TSPONPY5R
SCHEMBL21884024 0.92 TSPO (0.40) ADORA1CYP11B2TSPONPY5R
SCHEMBL21840849 0.92 TSPO (0.40) ADORA1CYP11B2TSPONPY5R
SCHEMBL21840840 0.92 TSPO (0.40) ADORA1CYP11B2TSPONPY5R
SCHEMBL21884031 0.92 TSPO (0.40) ADORA1CYP11B2TSPONPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210343947-A1 BENZONITRILE DERIVATIVE AND MANUFACTURING METHOD THEREFOR, INK COMPOSITION, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, LIGHT-EMITTING MATERIAL, CHARGE TRANSPORT MATERIAL, LIGHT-EMITTING THIN FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2021-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210343947-A1 BENZONITRILE DERIVATIVE AND MANUFACTURING METHOD THEREFOR, INK COMPOSITION, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, LIGHT-EMITTING MATERIAL, CHARGE TRANSPORT MATERIAL, LIGHT-EMITTING THIN FILM, AND ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, TCF4, SLC6A11 SQOR 2295/4885ADORA1 1824/4885MKNK1 4433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.