Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21343922 | 0.89 | — | — | |
| SCHEMBL21285089 | 0.86 | HIF1A (0.32) | MMP13ADAM17MMP1MMP2MMP9 | |
| SCHEMBL24092256 | 0.86 | CYP2D6 (0.34) | MEN1CYP1A2CYP2C9TSHRKMT2A | |
| SCHEMBL21285100 | 0.84 | HIF1A (0.33) | MMP13ADAM17MMP1MMP2MMP9 | |
| SCHEMBL21285105 | 0.83 | MMP13 (0.33) | MMP13ADAM17MMP1MMP2MMP9 | |
| SCHEMBL21285249 | 0.83 | HIF1A (0.31) | MEN1CYP1A2CYP2C9TSHRKMT2A | |
| SCHEMBL21285251 | 0.83 | CYP2D6 (0.31) | MEN1CYP1A2CYP2C9TSHRKMT2A | |
| SCHEMBL21285253 | 0.82 | HIF1A (0.30) | MEN1CYP1A2CYP2C9TSHRKMT2A | |
| SCHEMBL21285247 | 0.81 | — | — | |
| SCHEMBL21285031 | 0.81 | CYP1A2 (0.34) | MEN1CYP1A2CYP2C9TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542235-B2 | Herbicidal 3-azaspiro[5.5] undecane-8, 10-dione compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2023-01-03 | — | — | US | disclosed |
| US-20210139432-A1 | HERBICIDAL 3- AZASPIRO[5.5] UNDECANE-8, 10-DIONE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139432-A1 | HERBICIDAL 3- AZASPIRO[5.5] UNDECANE-8, 10-DIONE COMPOUNDS | DDT, DECR1, DHRS9 | MMP13 3740/4885ADAM17 2239/4885MMP1 2029/4885 |
| US-11542235-B2 | Herbicidal 3-azaspiro[5.5] undecane-8, 10-dione compounds | DDT, DECR1, DHRS9 | MMP13 3740/4885ADAM17 2239/4885MMP1 2029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.