Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
| ▸ | F3 | P13726 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16135284 | 0.97 | TRPV1 (0.42) | TRPV1F7F3PPARGFFAR1 | |
| SCHEMBL16135283 | 0.92 | GAA (0.42) | TRPV1GAAALDH1A1MAPTFAAH | |
| SCHEMBL16135277 | 0.92 | GAA (0.42) | TRPV1GAAALDH1A1MAPTFAAH | |
| SCHEMBL23345540 | 0.92 | GAA (0.42) | TRPV1GAAALDH1A1MAPTFAAH | |
| SCHEMBL16162777 | 0.88 | GAA (0.40) | TRPV1GAAALDH1A1FAAHMGLL | |
| SCHEMBL10384639 | 0.81 | MAPT (0.40) | GAAL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL499774 | 0.76 | GAA (0.45) | GAAMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL16135393 | 0.76 | RAB9A (0.39) | GAAL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL16135286 | 0.75 | HIF1A (0.49) | TRPV1F7F3CNR1CNR2 | |
| SCHEMBL5620989 | 0.71 | MAPT (0.40) | GAAL3MBTL1MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11833129-B2 | Thiophene compound for treatment of exfoliating glaucoma | AVOSCIENCE, LLC (US) | 2023-12-05 | — | — | US | disclosed |
| US-20210137876-A1 | LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR TREATMENT OF CANCER, NEUROLOGICAL DISORDERS, AND FIBROTIC DISORDERS | AVOSCIENCE, LLC (US) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210137876-A1 | LIPIDIC FURAN, PYRROLE, AND THIOPHENE COMPOUNDS FOR TREATMENT OF CANCER, NEUROLOGICAL DISORDERS, AND FIBROTIC DISORDERS | FAH, PHOSPHO1, FAP | TRPV1 1190/4885GAA 1793/4885F7 923/4885 |
| US-11833129-B2 | Thiophene compound for treatment of exfoliating glaucoma | TYMP, TDP1, TDP2 | TRPV1 1396/4885GAA 580/4885F7 1983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.