SCHEMBL23346902

SCHEMBL23346902

CC(C)(C)n1ccc2cc[nH]c21

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 1/20 0.36
▸ TAF1 P21675 1/20 0.36
▸ BRPF1 P55201 1/20 0.36
▸ CREBBP Q92793 1/20 0.36
▸ CECR2 Q9BXF3 1/20 0.36
▸ BRD9 Q9H8M2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23346865 0.81 BRD4 (0.33) BRD4TAF1BRPF1CREBBPCECR2
SCHEMBL24916152 0.76 — —
SCHEMBL17933517 0.76 — —
SCHEMBL25613389 0.72 GPR84 (0.40) —
SCHEMBL26596947 0.67 AOC3 (0.34) —
SCHEMBL23346672 0.67 BRD4 (0.37) BRD4
SCHEMBL24916388 0.67 BRD4 (0.36) BRD4TAF1BRPF1CREBBPCECR2
SCHEMBL25613021 0.66 AXL (0.32) BRD4
SCHEMBL22792595 0.63 BRD4 (0.33) BRD4TAF1BRPF1CREBBPCECR2
SCHEMBL26596944 0.63 RIPK2 (0.32) BRD4TAF1BRPF1CREBBPCECR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399355-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. 2023-12-14 — — US disclosed
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof Lakewood Amedex, Inc. (US) 2023-10-24 — — US disclosed
US-20210139522-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. 2021-05-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210139522-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF CFTR, ABCB11, CEL BRD4 4754/4885TAF1 2079/4885BRPF1 2281/4885
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof CAT, MPO, NISCH BRD4 4488/4885TAF1 3750/4885BRPF1 3507/4885
US-20230399355-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF CAT, MPO, NISCH BRD4 4488/4885TAF1 3750/4885BRPF1 3507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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