SCHEMBL23347759

SCHEMBL23347759

C[C@@H](Cc1cccc(I)c1)OC(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
THPO P40225 1/20 0.44
RAB9A P51151 1/20 0.44
HIF1A Q16665 1/20 0.44
IDO1 P14902 2/20 0.44
LMNA P02545 2/20 0.42
PMP22 Q01453 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CTSB P07858 1/20 0.42
NOS3 P29474 2/20 0.40
NOS1 P29475 2/20 0.40
NOS2 P35228 2/20 0.40
SLC7A5 Q01650 3/20 0.40
TACR1 P25103 1/20 0.39
MAPK8 P45983 1/20 0.39
TSHR P16473 2/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27804715 0.83 MAOA (0.43) RAB9ALMNANOS3NOS1NOS2
SCHEMBL16067485 0.83 POLB (0.50) RAB9AIDO1CTSBNOS3NOS1
SCHEMBL16067494 0.82 CYP1A2 (0.42) CYP1A2CYP2D6CYP2C19THPORAB9A
SCHEMBL28237997 0.82 SLC6A2 (0.50) CYP1A2CYP2D6RAB9ACTSBSLC7A5
SCHEMBL1811694 0.82 SLC6A2 (0.50) CYP1A2CYP2D6RAB9ACTSBSLC7A5
SCHEMBL28914994 0.82 SLC6A2 (0.50) CYP1A2CYP2D6RAB9ACTSBSLC7A5
SCHEMBL28937365 0.82 PTGES (0.46) IDO1CTSBTAAR1
SCHEMBL28937363 0.82 PTGES (0.46) IDO1CTSBTAAR1
SCHEMBL26816171 0.81 CTSB (0.40) CYP1A2CYP2D6CYP2C19THPORAB9A
SCHEMBL933328 0.80 CYP1A2 (0.47) CYP1A2CYP2D6CYP2C19THPORAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2968211-B1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME BIO PHARM SOLUTIONS CO LTD (KR) 2021-05-12 EP disclosed