Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.40 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.40 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972579 | 0.85 | PLA2G10 (0.47) | CYP1A2CYP2D6CYP2C19THPORAB9A | |
| SCHEMBL934633 | 0.81 | GRIA2 (0.49) | CYP1A2HIF1ALMNAPMP22 | |
| SCHEMBL28662062 | 0.81 | ADRB2 (0.45) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL24915424 | 0.81 | POLB (0.47) | IDO1CTSBMAPK8PLA2G10PLA2G2A | |
| SCHEMBL4683271 | 0.81 | SLC7A5 (0.43) | CYP2C19IDO1CTSB | |
| SCHEMBL16578231 | 0.81 | SLC7A5 (0.43) | CYP2C19IDO1CTSB | |
| SCHEMBL9989813 | 0.80 | SLC1A1 (0.55) | CYP2D6CYP2C19 | |
| SCHEMBL31324833 | 0.80 | PNMT (0.64) | IDO1PNMT | |
| SCHEMBL23347759 | 0.80 | CYP1A2 (0.44) | CYP1A2CYP2D6CYP2C19THPORAB9A | |
| SCHEMBL933832 | 0.79 | EPHX1 (0.49) | CYP1A2CYP2D6LMNAPMP22EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |