Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31619746 | 1.00 | CES1 (0.58) | CES1ALDH1A1CES2BCHEMCL1 | |
| SCHEMBL15673011 | 0.85 | ALDH1A1 (0.59) | ALDH1A1DNMT1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL20988450 | 0.84 | TYMS (0.61) | ALDH1A1DNMT1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13045525 | 0.82 | PABPC1 (0.50) | CES1ALDH1A1MCL1DNMT1KDM4E | |
| SCHEMBL6077039 | 0.82 | ALDH1A1 (0.56) | ALDH1A1DNMT1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL31619723 | 0.81 | CES1 (0.72) | CES1ALDH1A1CES2BCHEMCL1 | |
| SCHEMBL13045522 | 0.81 | PABPC1 (0.72) | CES1ALDH1A1CES2BCHEMCL1 | |
| SCHEMBL29456701 | 0.81 | PABPC1 (0.72) | CES1ALDH1A1CES2BCHEMCL1 | |
| SCHEMBL14680387 | 0.81 | PTPN1 (0.41) | CES1ALDH1A1CES2BCHEMCL1 | |
| SCHEMBL2328517 | 0.80 | ALDH1A1 (0.48) | ALDH1A1DNMT1KDM4ECASP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139417-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT | CANON KABUSHIKI KAISHA (JP) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139417-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT | CYP1A1, POU2F1, NFE2L2 | CES1 1428/4885ALDH1A1 252/4885CES2 1484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.