Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTC4S | Q16873 | 18/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1724841 | 0.89 | LTC4S (0.38) | LTC4S | |
| SCHEMBL27850795 | 0.87 | LTC4S (0.45) | LTC4S | |
| SCHEMBL12040183 | 0.83 | LTC4S (0.51) | LTC4S | |
| SCHEMBL27830993 | 0.80 | LTC4S (0.59) | LTC4S | |
| SCHEMBL232237 | 0.79 | SRD5A2 (0.56) | LTC4SSRD5A2RXRANR4A2 | |
| SCHEMBL230420 | 0.78 | LTC4S (0.43) | LTC4SSRD5A2RXRANR4A2 | |
| SCHEMBL231095 | 0.78 | LTC4S (0.42) | LTC4SSRD5A2RXRANR4A2 | |
| SCHEMBL1726608 | 0.76 | ACLY (0.36) | — | |
| SCHEMBL230136 | 0.75 | SRD5A2 (0.51) | LTC4SSRD5A2RXRANR4A2 | |
| SCHEMBL2743197 | 0.75 | LTC4S (0.43) | LTC4SSRD5A2RXRANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102341371-A | As LTC4Bis-aromatic compounds as synthase inhibitors | BIOLIPOX AB (SE) | 2012-02-01 | — | — | CN | disclosed |
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
| US-20110319431-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2011-12-29 | — | — | US | disclosed |
| US-20110319431-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2011-12-29 | — | — | US | disclosed |
| US-20110319431-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319431-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | LTC4S 1/4885SRD5A2 1138/4885RXRA 2238/4885 |
| US-20120004228-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | LTC4S 1/4885SRD5A2 564/4885RXRA 2078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.