Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29273412 | 0.83 | ALDH1A1 (0.38) | TDP1ELANEALDH1A1MCL1KDM4E | |
| SCHEMBL23355462 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4ECA1CA2CA12 | |
| SCHEMBL23355436 | 0.76 | JAK1 (0.39) | TDP1ALDH1A1KDM4EMAPK14MEN1 | |
| SCHEMBL30204830 | 0.76 | TDP1 (0.44) | TDP1ALDH1A1KDM4ECA1CA2 | |
| SCHEMBL20620683 | 0.73 | HPGD (0.42) | TDP1ELANEALDH1A1KDM4ECA1 | |
| SCHEMBL16781951 | 0.72 | KDM4E (0.46) | TDP1ALDH1A1KDM4ENOTUMCA1 | |
| SCHEMBL23355447 | 0.72 | MAPK14 (0.43) | ALDH1A1KDM4EMAPK14MEN1HPGD | |
| SCHEMBL30933433 | 0.72 | MAPK14 (0.43) | ALDH1A1KDM4EMAPK14MEN1HPGD | |
| SCHEMBL23355414 | 0.71 | RAB9A (0.50) | TDP1ALDH1A1KDM4ECA1CA2 | |
| SCHEMBL16808002 | 0.70 | KDM4E (0.50) | TDP1ALDH1A1KDM4ECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996788-B | Anthelmintic heterocyclic compounds | 勃林格殷格翰动物保健美国公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112996788-A | Anthelmintic heterocyclic compounds | 勃林格殷格翰动物保健美国公司 | 2021-06-18 | — | — | CN | disclosed |
| EP-3820870-A1 | ANTHELMINTHIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-05-19 | — | — | EP | disclosed |