Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23355447 | 1.00 | MAPK14 (0.43) | MAPK14ALDH1A1MAPTTP53RORC | |
| SCHEMBL23355436 | 0.92 | JAK1 (0.39) | MAPK14ALDH1A1MAPTJAK1TYK2 | |
| SCHEMBL29273416 | 0.87 | RORC (0.41) | RORC | |
| SCHEMBL29273408 | 0.78 | TTR (0.45) | MAPK14ALDH1A1MAPTTP53RORC | |
| SCHEMBL30933439 | 0.76 | ALDH1A1 (0.36) | MAPK14ALDH1A1MAPTTP53KDM4E | |
| SCHEMBL23355444 | 0.76 | ALDH1A1 (0.36) | MAPK14ALDH1A1MAPTTP53KDM4E | |
| SCHEMBL23355474 | 0.72 | TDP1 (0.42) | MAPK14ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL9049556 | 0.71 | MAPT (0.43) | MAPK14ALDH1A1MAPTTP53JAK1 | |
| SCHEMBL953252 | 0.70 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL23355434 | 0.70 | GAA (0.46) | ALDH1A1JAK1TYK2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996788-B | Anthelmintic heterocyclic compounds | 勃林格殷格翰动物保健美国公司 | 2024-07-16 | — | — | CN | disclosed |