SCHEMBL23359754

SCHEMBL23359754

CN(c1ccnc2ccccc12)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 12/20 0.52
USP30 Q70CQ3 3/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29862979 1.00 GPR119 (0.52) GPR119USP30MEN1KMT2A
SCHEMBL28834231 0.94 USP30 (0.52) GPR119USP30MEN1KMT2A
SCHEMBL28834232 0.94 USP30 (0.52) GPR119USP30MEN1KMT2A
SCHEMBL23360292 0.93 GPR119 (0.49) GPR119USP30MEN1KMT2A
SCHEMBL28834334 0.87 USP30 (0.48) GPR119USP30
SCHEMBL28834263 0.87 USP30 (0.48) GPR119USP30
SCHEMBL28834262 0.87 USP30 (0.48) GPR119USP30
SCHEMBL29862921 0.87 USP30 (0.48) GPR119USP30
SCHEMBL29862815 0.87 USP30 (0.48) GPR119USP30
SCHEMBL23707488 0.86 IDO1 (0.52) GPR119MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055014-B1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORP (KR) 2025-04-30 EP disclosed
US-11655235-B2 Pyrrolidine and piperidine compounds YUHAN CORPORATION (KR) 2023-05-23 US disclosed
EP-4055014-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS Yuhan Corporation (KR) 2022-09-14 EP disclosed
CN-114867719-A Pyrrolidine and piperidine compounds 柳韩洋行 2022-08-05 CN disclosed
US-20210147386-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORPORATION (KR) 2021-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655235-B2 Pyrrolidine and piperidine compounds FAP, APC, VHL GPR119 1940/4885USP30 1231/4885MEN1 2004/4885
US-20210147386-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS FAP, APC, VHL GPR119 1940/4885USP30 1231/4885MEN1 2004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.