Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.54 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13208856 | 0.97 | — | — | |
| SCHEMBL206647 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2565646 | 0.94 | ALDH1A1 (0.58) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL31318946 | 0.94 | DPP4 (0.55) | DPP4F2LMNAADRA2AADRA2C | |
| Nitrogen SCHEMBL28373188 | 0.92 | DPP4 (0.52) | DPP4F2LMNAADRA2AADRA2C | |
| Carbamic Acid SCHEMBL19359124 | 0.87 | LMNA (0.52) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL27951259 | 0.76 | GSR (0.40) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL27315564 | 0.76 | MAOA (0.46) | DPP4F2LMNAADRA2AADRA2C | |
| Diphenylmethanol SCHEMBL29571414 | 0.75 | SMN1; SMN2 (0.58) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| Aminodiphenylmethane SCHEMBL9596876 | 0.75 | DPP4 (0.61) | DPP4F2LMNAADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110803996-B | Synthesis method of hydroxybenzylamine | 台州市创源工业技术有限公司 | 2022-01-11 | — | — | CN | disclosed |
| WO-2021093426-A1 | METHOD FOR SYNTHESIZING HYDROXYBENZYLAMINE | 台州市创源工业技术有限公司 | 2021-05-20 | — | — | WO | disclosed |
| CN-110803996-A | Synthesis method of hydroxybenzylamine | 台州市创源工业技术有限公司 | 2020-02-18 | — | — | CN | disclosed |