SCHEMBL23364873

SCHEMBL23364873

CC[C@@]1(O)CCc2ccc(Cl)nc21

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.38
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
WEE1 P30291 6/20 0.32
EGFR P00533 1/20 0.32
CYP3A4 P08684 1/20 0.32
PLK1 P53350 1/20 0.32
MAP3K19 Q56UN5 1/20 0.32
PLK3 Q9H4B4 1/20 0.32
PLK2 Q9NYY3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30496896 1.00 MAP3K14 (0.38) MAP3K14ESR1ESR2GRIN2DGRIN3B
SCHEMBL29828611 1.00 MAP3K14 (0.38) MAP3K14ESR1ESR2GRIN2DGRIN3B
SCHEMBL22532060 1.00 MAP3K14 (0.38) MAP3K14ESR1ESR2GRIN2DGRIN3B
SCHEMBL23376737 0.90 MAP3K14 (0.36) MAP3K14ESR1ESR2GRIN2DGRIN3B
SCHEMBL25031335 0.85 DRD2 (0.35) MAP3K14ESR1ESR2WEE1EGFR
SCHEMBL24881427 0.83 MAP3K14 (0.32) MAP3K14ESR1ESR2WEE1EGFR
SCHEMBL21334000 0.83 MAP3K14 (0.32) MAP3K14ESR1ESR2WEE1EGFR
SCHEMBL21332753 0.83 MAP3K14 (0.32) MAP3K14ESR1ESR2WEE1EGFR
SCHEMBL21349674 0.83 MAP3K14 (0.32) MAP3K14ESR1ESR2WEE1EGFR
SCHEMBL23364874 0.83 MAP3K14 (0.32) MAP3K14ESR1ESR2WEE1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028363-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL RECURIUM IP HOLDINGS LLC (US) 2026-01-29 US disclosed
US-12410204-B2 Chiral synthesis of a tertiary alcohol RECURIUM IP HOLDINGS, LLC (US) 2025-09-09 US disclosed
US-20230234956-A1 METHODS OF MAKING WEE1 INHIBITOR COMPOUNDS RECURIUM IP HOLDINGS, LLC 2023-07-27 US disclosed
US-20230234956-A1 METHODS OF MAKING WEE1 INHIBITOR COMPOUNDS RECURIUM IP HOLDINGS, LLC 2023-07-27 US disclosed
US-20230234956-A1 METHODS OF MAKING WEE1 INHIBITOR COMPOUNDS RECURIUM IP HOLDINGS, LLC 2023-07-27 US disclosed
EP-4153591-A1 METHODS OF MAKING WEE1 INHIBITOR COMPOUNDS Recurium IP Holdings, LLC (US) 2023-03-29 EP disclosed
US-20230002426-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL RECURIUM IP HOLDINGS, LLC 2023-01-05 US disclosed
US-20230002426-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL RECURIUM IP HOLDINGS, LLC 2023-01-05 US disclosed
EP-4045486-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL Recurium IP Holdings, LLC (US) 2022-08-24 EP disclosed
CN-114829343-A Chiral synthesis of tertiary alcohols 里科瑞尔姆IP控股有限责任公司 2022-07-29 CN disclosed
WO-2021252667-A1 METHODS OF MAKING WEE1 INHIBITOR COMPOUNDS RECURIUM IP HOLDINGS, LLC (US) 2021-12-16 WO disclosed
WO-2021252667-A1 METHODS OF MAKING WEE1 INHIBITOR COMPOUNDS RECURIUM IP HOLDINGS, LLC (US) 2021-12-16 WO disclosed
WO-2021097139-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL RECURIUM IP HOLDINGS, LLC (US) 2021-05-20 WO disclosed
WO-2021097139-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL RECURIUM IP HOLDINGS, LLC (US) 2021-05-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12410204-B2 Chiral synthesis of a tertiary alcohol ADH1A, ADH1C, ADH5 MAP3K14 755/4885ESR1 895/4885ESR2 1185/4885
US-20230234956-A1 METHODS OF MAKING WEE1 INHIBITOR COMPOUNDS WEE1, WEE2, CCNE1 MAP3K14 394/4885ESR1 2847/4885ESR2 2943/4885
US-20260028363-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL ADH1A, ADH1C, ADH5 MAP3K14 873/4885ESR1 750/4885ESR2 2140/4885
US-20230002426-A1 CHIRAL SYNTHESIS OF A TERTIARY ALCOHOL ADH1A, ADH1C, ADH5 MAP3K14 755/4885ESR1 895/4885ESR2 1185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.