Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8168464 | 0.82 | CYP19A1 (0.44) | PTGS2PTGS1GABRA5HSP90AA1ALDH1A1 | |
| SCHEMBL13960573 | 0.81 | CYP2A6 (0.44) | KMT2AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL2929388 | 0.81 | NOTUM (0.49) | PTGS2GABRA5HSP90AA1MEN1KMT2A | |
| SCHEMBL8306253 | 0.81 | GABRA5 (0.42) | PTGS2PTGS1GABRA5HSP90AA1MEN1 | |
| SCHEMBL3213310 | 0.81 | PTGS2 (0.41) | PTGS2PTGS1GABRA5HSP90AA1MEN1 | |
| SCHEMBL28139688 | 0.81 | NOTUM (0.44) | PTGS2PTGS1GABRA5HSP90AA1MEN1 | |
| SCHEMBL4973045 | 0.80 | PTGS2 (0.41) | PTGS2PTGS1GABRA5HSP90AA1MEN1 | |
| SCHEMBL27819710 | 0.80 | KDM4E (0.49) | PTGS2PTGS1GABRA5HSP90AA1ALDH1A1 | |
| SCHEMBL7372479 | 0.80 | GABRA5 (0.33) | PTGS2PTGS1GABRA5HSP90AA1CYP19A1 | |
| SCHEMBL5775916 | 0.78 | NOTUM (0.46) | PTGS2GABRA5HSP90AA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11011712-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-05-18 | — | — | US | disclosed |
| CN-104781271-B | Polynucleotides having bioreversible groups | 加利福尼亚大学董事会 | 2018-07-06 | — | — | CN | disclosed |
| CN-107109405-A | Polynucleotide constructs with Bioreversible and abiotic invertibity group | 索尔斯蒂斯生物有限公司 | 2017-08-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11011712-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | DPYD, DCTD, TYMP | PTGS2 3525/4885PTGS1 2771/4885GABRA5 4300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.