Diphenylamine

Diphenylamine

SCHEMBL233665

N.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.92
ALDH1A1 P00352 7/20 0.86
TDP1 Q9NUW8 7/20 0.86
TSHR P16473 4/20 0.86
ALOX12 P18054 3/20 0.86
L3MBTL1 Q9Y468 3/20 0.86
ALOX15 P16050 2/20 0.86
MAPK1 P28482 2/20 0.86
PTGS1 P23219 1/20 0.86
SLC6A2 P23975 1/20 0.86
PTGS2 P35354 1/20 0.86
HTR2B P41595 1/20 0.86
MAPT P10636 7/20 0.71
MEN1 O00255 5/20 0.71
KMT2A Q03164 5/20 0.71
AR P10275 1/20 0.71
CYP3A4 P08684 5/20 0.63
HPGD P15428 2/20 0.63
HTT P42858 2/20 0.63
CYP1A2 P05177 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL1555489 1.00 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1TSHRALOX12
N,N'-Diphenyl-P-Phenylenediamine SCHEMBL8465009 0.96 ALDH1A1 (0.93) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL6470076 0.96 HSD17B10 (0.86) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL8852775 0.96 HSD17B10 (0.86) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL1619083 0.96 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL3003404 0.96 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL6828443 0.96 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL301493 0.96 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL229 0.96 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL23295988 0.92 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1TSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1730468-B1 Method for detecting explosives based on certain oxidants MISTRAL DETECTION LTD (IL) 2014-06-04 EP claimed
US-7846740-B2 Method and kit for detecting explosive substances containing certain oxidants MISTRAL DETECTION LTD. (IL) 2010-12-07 US claimed
US-20080182334-A1 Method and Kit For Detecting Explosive Substances Containing Certain Oxidants MISTRAL, INC. 2008-07-31 US claimed
EP-1730468-A2 METHOD AND KIT FOR DETECTING EXPLOSIVE SUBSTANCES CONTAINING CERTAIN OXIDANTS Mistral Detection Ltd. (IL) 2006-12-13 EP claimed
WO-2005089058-A2 METHOD AND KIT FOR DETECTING EXPLOSIVE SUBSTANCES CONTAINING CERTAIN OXIDANTS MISTRAL DETECTION LTD. (IL) 2005-09-29 WO claimed
CN-118063494-A Organic electroluminescent compound with core structure of boron-containing polycyclic aza-aromatic hydrocarbon and application thereof 吉林省元合电子材料有限公司 2024-05-24 CN disclosed
EP-4370913-A1 METHOD FOR ANALYZING TRACE LEVELS OF SEMI-VOLATILE NITROSAMINES IN SOLID SAMPLES Merck Sharp & Dohme LLC (US) 2024-05-22 EP disclosed
US-20230100458-A1 NOVEL ANTHRANILIC AMIDES AND THE USE THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-03-30 US disclosed
WO-2023287670-A1 METHOD FOR ANALYZING TRACE LEVELS OF SEMI-VOLATILE NITROSAMINES IN SOLID SAMPLES MERCK SHARP & DOHME LLC (US) 2023-01-19 WO disclosed
US-11465978-B2 Anthranilic amides and the use thereof THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2022-10-11 US disclosed
EP-3043790-B1 NOVEL ANTHRANILIC AMIDES AND THE USE THEREOF THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2021-05-26 EP disclosed
CN-112442409-A Mixed soap-based electrical appliance contact lubricating grease 茂名南海长城石化有限公司 2021-03-05 CN disclosed
US-20080182334-A1 Method and Kit For Detecting Explosive Substances Containing Certain Oxidants MISTRAL, INC. 2008-07-31 US disclosed
CN-100399547-C Flexible wiring board for tape carrier package having improved flame resistance UBE INDUSTRIES (JP) 2008-07-02 CN disclosed
EP-1730468-A2 METHOD AND KIT FOR DETECTING EXPLOSIVE SUBSTANCES CONTAINING CERTAIN OXIDANTS Mistral Detection Ltd. (IL) 2006-12-13 EP disclosed
CN-1767176-A Flexible wiring board for tape carrier package having improved flame resistance UBE INDUSTRIES (JP) 2006-05-03 CN disclosed
WO-2005089058-A2 METHOD AND KIT FOR DETECTING EXPLOSIVE SUBSTANCES CONTAINING CERTAIN OXIDANTS MISTRAL DETECTION LTD. (IL) 2005-09-29 WO disclosed
CN-1068123-C Polyester precoated photosensitive plate and preparation method thereof LI SANBAO (CN) 2001-07-04 CN disclosed
EP-0070436-B1 STABILIZER-CONTAINING REACTIVE COMPONENTS FOR PU FOAMS, STABILIZERS AND PROCESS FOR THE PREPARATION OF THE STABILIZERS BAYER AG (DE) 1986-02-26 EP disclosed
EP-0070436-A1 Stabilizer-containing reactive components for PU foams, stabilizers and process for the preparation of the stabilizers BAYER AG (DE) 1983-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230100458-A1 NOVEL ANTHRANILIC AMIDES AND THE USE THEREOF API5, MAPKAPK5, MAP3K5 HSD17B10 2240/4885ALDH1A1 605/4885TDP1 4264/4885
US-11465978-B2 Anthranilic amides and the use thereof MAPKAPK5, MAP3K5, API5 HSD17B10 2082/4885ALDH1A1 392/4885TDP1 4383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.