⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13840155 | 0.78 | — | — | |
| SCHEMBL13862155 | 0.73 | ALDH1A1 (0.44) | — | |
| SCHEMBL22549288 | 0.72 | — | — | |
| SCHEMBL23367239 | 0.71 | — | — | |
| SCHEMBL8198026 | 0.70 | — | — | |
| SCHEMBL19574093 | 0.70 | GLO1 (0.31) | — | |
| SCHEMBL1636754 | 0.68 | — | — | |
| SCHEMBL23134836 | 0.67 | ALOX15 (0.31) | — | |
| SCHEMBL24200053 | 0.67 | ALOX15 (0.30) | — | |
| SCHEMBL8439010 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822265-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer AG (DE) | 2021-05-19 | — | — | EP | disclosed |