Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | C1S | P09871 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 4/20 | 0.31 |
| ▸ | F2 | P00734 | 3/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14826019 | 0.78 | PRSS1 (0.32) | PRSS1PRSS2C1SPRSS3PLAU | |
| SCHEMBL18793319 | 0.75 | PRSS1 (0.36) | PRSS1PRSS2C1SPRSS3PLAU | |
| SCHEMBL15979054 | 0.73 | KHK (0.39) | — | |
| SCHEMBL11770568 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL10144932 | 0.71 | NOS3 (0.38) | — | |
| SCHEMBL18951964 | 0.68 | LMNA (0.41) | — | |
| SCHEMBL12569525 | 0.68 | PRSS1 (0.38) | PRSS1PRSS2C1SPRSS3F10 | |
| SCHEMBL10144270 | 0.68 | SLC9A1 (0.37) | — | |
| SCHEMBL18793352 | 0.68 | POLB (0.38) | PRSS1PRSS2C1SPRSS3F10 | |
| SCHEMBL14826020 | 0.67 | SLC9A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3822270-A1 | NOVEL HETEROCYCLE DERIVATIVE | JW Pharmaceutical Corporation (KR) | 2021-05-19 | — | — | EP | disclosed |