SCHEMBL2337249

SCHEMBL2337249

NCC1CCN(C(=O)O)C1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PLG P00747 1/20 0.42
PLAT P00750 1/20 0.42
LMNA P02545 1/20 0.42
CHRM2 P08172 4/20 0.41
CHRM1 P11229 4/20 0.41
CHRM3 P20309 4/20 0.41
NCF1 P14598 1/20 0.40
TACR3 P29371 1/20 0.39
DPP7 Q9UHL4 3/20 0.36
DPP8 Q6V1X1 1/20 0.36
TPSAB1 Q15661 2/20 0.35
TPSD1 Q9BZJ3 2/20 0.35
TPSG1 Q9NRR2 2/20 0.35
CYP2D6 P10635 1/20 0.35
CPN1 P15169 1/20 0.34
CPB2 Q96IY4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL790440 1.00 PLG (0.42) PLGPLATLMNACHRM2CHRM1
SCHEMBL3155411 1.00 PLG (0.42) PLGPLATLMNACHRM2CHRM1
Hydrochloric Acid SCHEMBL25287438 0.98 PLG (0.41) PLGPLATLMNACHRM2CHRM1
Hydrochloric Acid SCHEMBL25248778 0.98 PLG (0.41) PLGPLATLMNACHRM2CHRM1
Tert-Butanol SCHEMBL28550813 0.91 CHRM2 (0.43) PLGPLATLMNACHRM2CHRM1
SCHEMBL1694214 0.88 ITGB3 (0.43) PLGPLATLMNACHRM2CHRM1
SCHEMBL1694358 0.88 ITGB3 (0.43) PLGPLATLMNACHRM2CHRM1
SCHEMBL856443 0.88 ITGB3 (0.43) PLGPLATLMNACHRM2CHRM1
SCHEMBL600521 0.87 PLG (0.50) PLGPLATLMNACHRM2CHRM1
Hydrochloric Acid SCHEMBL5249863 0.85 PLG (0.48) PLGPLATLMNACHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104080335-A Certain chemical entities, compositions, and methods QIAN XIANGPING 2014-10-01 CN claimed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 EP disclosed
WO-2024105007-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2024-05-23 WO disclosed
US-11958833-B2 Compounds MISSION THERAPEUTICS LIMITED (GB) 2024-04-16 US disclosed
EP-3730484-B1 INDOLEAMINE-2,3-DIOXYGENASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF HINOVA PHARMACEUTICALS INC (CN) 2024-02-28 EP disclosed
CN-117586180-A Compounds useful as inhibitors of voltage-gated sodium channels 广州费米子科技有限责任公司 2024-02-23 CN disclosed
CN-117412964-A Substituted heterocyclic compounds and their use 首药控股(北京)股份有限公司 2024-01-16 CN disclosed
WO-2023244917-A1 1,8-NAPHTHYRIDIN-2-ONE HETEROBIFUNCTIONAL BCL6 DEGRADERS Treeline Biosciences, Inc. (US) 2023-12-21 WO disclosed
EP-4274569-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2023-11-15 EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 WO disclosed
WO-2011056635-A1 BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS GLAXOSMITHKLINE LLC (US) 2011-05-12 WO disclosed
CN-102007128-A Tricyclic antibiotics ACTELION PHARMACEUTICALS LTD 2011-04-06 CN disclosed
CN-101678015-A Pyrrolo (3, 2, 1-ij) quinoline-4-one derivatives for treating tuberculosis GLAXO GROUP LTD 2010-03-24 CN disclosed
US-20090281075-A1 ISOMERIC PURINONES AND 1H-IMIDAZOPYRIDINONES AS PKC-THETA INHIBITORS PHARMACOPEIA, INC. (US) 2009-11-12 US disclosed
WO-2009062059-A2 ISOMERIC PURINONES AND 1H-IMIDAZOPYRIDINONES AS PKC-THETA INHIBITORS PHARMACOPEIA, INC. (US) 2009-05-14 WO disclosed
CN-101346379-A Per-cyclic tricyclic compounds useful as antibacterial agents GLAXO GROUP LTD (GB) 2009-01-14 CN disclosed
US-20070259855-A1 THIAZOLYL-DIHYDRO-INDAZOLE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-11-08 US disclosed
EP-1784393-A1 QUINAZOLINES USEFUL AS MODULATORS OF ION CHANNELS Vertex Pharmaceuticals Incorporated (US) 2007-05-16 EP disclosed
WO-2006028904-A9 QUINAZOLINES USEFUL AS MODULATORS OF ION CHANNELS VERTEX PHARMA (US) 2006-06-22 WO disclosed
WO-2006028904-A1 QUINAZOLINES USEFUL AS MODULATORS OF ION CHANNELS VERTEX PHARMACEUTICALS INCORPORATED (US) 2006-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281075-A1 ISOMERIC PURINONES AND 1H-IMIDAZOPYRIDINONES AS PKC-THETA INHIBITORS PRKCE, PRKCZ, PRKCQ PLG 2714/4885PLAT 1951/4885LMNA 1375/4885
US-20070259855-A1 THIAZOLYL-DIHYDRO-INDAZOLE ROR1, RORB, RORA PLG 3508/4885PLAT 3862/4885LMNA 3473/4885
US-11958833-B2 Compounds USP30, USP20, USP10 PLG 3553/4885PLAT 4602/4885LMNA 2533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.