Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PTGFR | P43088 | 1/20 | 0.42 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.42 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23133587 | 0.79 | HCAR3 (0.61) | NR1H4EPHX2GAAHTTKDM4E | |
| SCHEMBL6044645 | 0.77 | HCAR3 (0.72) | MAPTHCAR3MEN1KMT2A | |
| SCHEMBL6987179 | 0.76 | HCAR3 (0.56) | NR1H4EPHX2GAAHTTKDM4E | |
| SCHEMBL2424765 | 0.76 | ALDH1A1 (0.43) | GAAHTTKDM4EGFERALDH1A1 | |
| SCHEMBL1711030 | 0.75 | HDAC8 (0.59) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL15412525 | 0.75 | HCAR3 (0.62) | EPHX2GAAHTTKDM4EGFER | |
| SCHEMBL11255414 | 0.75 | HCAR3 (0.62) | EPHX2GAAHTTKDM4EGFER | |
| SCHEMBL8114921 | 0.74 | RAB9A (0.50) | GAAHTTKDM4EGFERALDH1A1 | |
| SCHEMBL15634988 | 0.74 | CTSV (0.40) | NR1H4EPHX2KDM4EALDH1A1MAPT | |
| SCHEMBL11262794 | 0.74 | HCAR3 (0.61) | EPHX2GAAHTTKDM4EGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021093817-A1 | IMMUNOMODULATORY COMPOUNDS, COMPOSITION AND APPLICATION THEREOF | 杭州和正医药有限公司 | 2021-05-20 | — | — | WO | disclosed |