Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | BPGM | P07738 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335008 | 0.82 | KMO (0.44) | KMORARBALDH1A1EDNRBEDNRA | |
| SCHEMBL2337473 | 0.82 | KMO (0.40) | KMORARBALDH1A1EDNRBEDNRA | |
| SCHEMBL2338601 | 0.81 | KMO (0.45) | KMORARBALDH1A1RAF1PLAT | |
| SCHEMBL2342381 | 0.79 | KMO (0.41) | KMORARBALDH1A1EDNRBEDNRA | |
| SCHEMBL2337594 | 0.79 | — | — | |
| SCHEMBL2332600 | 0.71 | KMO (0.42) | KMOALDH1A1RAF1 | |
| SCHEMBL2340435 | 0.71 | ALDH1A1 (0.42) | KMOALDH1A1RAF1 | |
| SCHEMBL2332112 | 0.71 | KMO (0.39) | KMORARBALDH1A1EDNRBEDNRA | |
| SCHEMBL2336517 | 0.70 | KMO (0.42) | KMORARBALDH1A1 | |
| SCHEMBL1935751 | 0.69 | NOTUM (0.45) | KMOALDH1A1RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318776-B2 | Pyridine compound, pesticidal composition and method of controlling pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-11-27 | — | — | US | disclosed |
| US-8318776-B2 | Pyridine compound, pesticidal composition and method of controlling pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-11-27 | — | — | US | disclosed |
| EP-2215086-B1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL CO (JP) | 2011-08-24 | — | — | EP | disclosed |
| US-20100286148-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286148-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-2215086-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | Sumitomo Chemical Company, Limited (JP) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009066786-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286148-A1 | PYRIDINE COMPOUND, PESTICIDAL COMPOSITION AND METHOD OF CONTROLLING PEST | C5, PRDX1, PLPBP | KMO 157/4885RARB 4771/4885ALDH1A1 2627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.