SCHEMBL23376402

SCHEMBL23376402

CC1(C)c2ccccc2-c2c(-c3ccc(N(c4ccc(-c5ccc(-c6cccc7c6oc6ccccc67)c6ccccc56)cc4)c4cccc5c4-c4ccccc4C5(C)C)cc3)cccc21

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.38
PRKDC P78527 3/20 0.31
MEN1 O00255 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
PGR P06401 1/20 0.31
AVPR1A P37288 1/20 0.30
PIK3CD O00329 1/20 0.30
PIK3CB P42338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23376199 0.97 ALOX5 (0.39) ALOX5PRKDCMEN1CYP2C19KMT2A
SCHEMBL23376055 0.95 ALOX5 (0.42) ALOX5PRKDCMEN1CYP2C19KMT2A
SCHEMBL23376509 0.94 ALOX5 (0.37) ALOX5PRKDCMEN1CYP2C19KMT2A
SCHEMBL23376404 0.93 ALOX5 (0.38) ALOX5PRKDCAVPR1A
SCHEMBL16858158 0.93 ALOX5 (0.43) ALOX5PRKDCMEN1CYP2C19KMT2A
SCHEMBL21446359 0.92 ALOX5 (0.38) ALOX5PRKDCAVPR1A
SCHEMBL21446209 0.92 ALOX5 (0.43) ALOX5PRKDCMEN1CYP2C19KMT2A
SCHEMBL21368098 0.91 ALOX5 (0.39) ALOX5PRKDCMEN1CYP2C19KMT2A
SCHEMBL16801888 0.91 ALOX5 (0.38) ALOX5PRKDCMEN1CYP2C19KMT2A
SCHEMBL21446365 0.90 ALOX5 (0.37) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210147375-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147375-A1 MATERIALS FOR ELECTRONIC DEVICES PNMT, EFNA1, TES ALOX5 2210/4885PRKDC 1765/4885MEN1 949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.